GO Annotations Graph

• Symbol: Cd63
• Name: CD63 antigen
• ID: MGI:99529

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:166710
Molecular Function	GO:0005515	protein binding	IPI	J:101236
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:73065
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0031904	endosome lumen	ISO	J:164563
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0010008	endosome membrane	ISO	J:94651
Cellular Component	GO:0070062	extracellular exosome	ISO	J:155856
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:236095
Cellular Component	GO:0005770	late endosome	IDA	J:90042
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005764	lysosome	ISO	J:155856
Cellular Component	GO:0005764	lysosome	IDA	J:236095
Cellular Component	GO:0005764	lysosome	IDA	J:90042
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0032585	multivesicular body membrane	ISO	J:164563
Cellular Component	GO:0097487	multivesicular body, internal vesicle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0035646	endosome to melanosome transport	ISO	J:164563
Biological Process	GO:0030855	epithelial cell differentiation	ISO	J:155856
Biological Process	GO:0010633	negative regulation of epithelial cell migration	ISO	J:155856
Biological Process	GO:0050931	pigment cell differentiation	IMP	J:210084
Biological Process	GO:0048757	pigment granule maturation	ISO	J:164563
Biological Process	GO:0043473	pigmentation	IMP	J:210084
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:155856
Biological Process	GO:0045807	positive regulation of endocytosis	ISO	J:155856
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0002092	positive regulation of receptor internalization	ISO	J:164563
Biological Process	GO:0008104	protein localization	ISO	J:101236
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	ISO	J:101236
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	ISO	J:164563
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	IMP	J:199599