GO Annotations Graph

• Symbol: Mef2a
• Name: myocyte enhancer factor 2A
• ID: MGI:99532

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:110295
Molecular Function	GO:0003682	chromatin binding	IDA	J:171727
Molecular Function	GO:0003682	chromatin binding	IDA	J:133573
Molecular Function	GO:0003677	DNA binding	IDA	J:50069
Molecular Function	GO:0003677	DNA binding	IDA	J:95038
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:110295
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:110295
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:50069
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:77997
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:155856
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:171727
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:172903
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0035035	histone acetyltransferase binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0042826	histone deacetylase binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:160383
Molecular Function	GO:0005515	protein binding	IPI	J:306710
Molecular Function	GO:0005515	protein binding	IPI	J:92922
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	IPI	J:148054
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:210946
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:183633
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:4385
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:165849
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:172903
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:95038
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:122033
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:133573
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IC	J:77997
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005634	nucleus	IDA	J:183633
Cellular Component	GO:0005634	nucleus	IDA	J:37685
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0061337	cardiac conduction	IMP	J:79973
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:155856
Biological Process	GO:0048813	dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0006351	DNA-templated transcription	ISO	J:164563
Biological Process	GO:0070375	ERK5 cascade	ISO	J:164563
Biological Process	GO:0007507	heart development	IBA	J:265628
Biological Process	GO:0000165	MAPK cascade	ISO	J:164563
Biological Process	GO:0000002	mitochondrial genome maintenance	IMP	J:79973
Biological Process	GO:0048311	mitochondrion distribution	IMP	J:79973
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:92922
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:262205
Biological Process	GO:0046326	positive regulation of glucose import	IDA	J:92922
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:110295
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:162523
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36282
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:36282
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:77997
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:50069
Biological Process	GO:0055005	ventricular cardiac myofibril assembly	IMP	J:79973