GO Annotations Graph

• Symbol: Glp1r
• Name: glucagon-like peptide 1 receptor
• ID: MGI:99571

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	ISO	J:155856
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004967	glucagon receptor activity	IBA	J:265628
Molecular Function	GO:0044508	glucagon-like peptide 1 receptor activity	ISO	J:164563
Molecular Function	GO:0044508	glucagon-like peptide 1 receptor activity	IBA	J:265628
Molecular Function	GO:0017046	peptide hormone binding	ISO	J:155856
Molecular Function	GO:0017046	peptide hormone binding	IBA	J:265628
Molecular Function	GO:0001653	peptide receptor activity	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	TAS	J:60180
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0008306	associative learning	ISO	J:155856
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:164563
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007631	feeding behavior	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0046879	hormone secretion	ISO	J:155856
Biological Process	GO:0046879	hormone secretion	IMP	J:198358
Biological Process	GO:0030073	insulin secretion	ISO	J:155856
Biological Process	GO:0007611	learning or memory	IMP	J:85361
Biological Process	GO:0007611	learning or memory	ISO	J:155856
Biological Process	GO:0007613	memory	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0045776	negative regulation of blood pressure	IMP	J:198358
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	TAS	J:60180
Biological Process	GO:0045777	positive regulation of blood pressure	IDA	J:189274
Biological Process	GO:0045777	positive regulation of blood pressure	ISO	J:155856
Biological Process	GO:0045777	positive regulation of blood pressure	IBA	J:265628
Biological Process	GO:0045597	positive regulation of cell differentiation	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0045823	positive regulation of heart contraction	ISO	J:155856
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0031204	post-translational protein targeting to membrane, translocation	IMP	J:198358
Biological Process	GO:0051924	regulation of calcium ion transport	ISO	J:155856
Biological Process	GO:0008016	regulation of heart contraction	IMP	J:83707
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	ISO	J:155856
Biological Process	GO:0009749	response to glucose	ISO	J:155856
Biological Process	GO:1990911	response to psychosocial stress	IMP	J:60181
Biological Process	GO:0007165	signal transduction	IEA	J:60000