Fgf8 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fgf8
fibroblast growth factor 8
MGI:99604

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042056	chemoattractant activity	ISO	J:155856
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	IEA	J:72247
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0008083	growth factor activity	IBA	J:265628
Molecular Function	GO:0005105	type 1 fibroblast growth factor receptor binding	ISO	J:164563
Molecular Function	GO:0005105	type 1 fibroblast growth factor receptor binding	IBA	J:265628
Molecular Function	GO:0005111	type 2 fibroblast growth factor receptor binding	ISO	J:164563
Molecular Function	GO:0005111	type 2 fibroblast growth factor receptor binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0035909	aorta morphogenesis	IGI	J:172023
Biological Process	GO:0035909	aorta morphogenesis	IGI	J:172023
Biological Process	GO:0035909	aorta morphogenesis	IGI	J:172023
Biological Process	GO:0006915	apoptotic process	IMP	J:109474
Biological Process	GO:0006915	apoptotic process	IMP	J:109474
Biological Process	GO:0006915	apoptotic process	IMP	J:109474
Biological Process	GO:0006915	apoptotic process	IMP	J:109474
Biological Process	GO:0006915	apoptotic process	IGI	J:102854
Biological Process	GO:0006915	apoptotic process	IGI	J:102854
Biological Process	GO:0006915	apoptotic process	IMP	J:109474
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:114854
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:114854
Biological Process	GO:0060348	bone development	ISO	J:164563
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:100584
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	IGI	J:100584
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	IGI	J:89200
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	IMP	J:92205
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	IMP	J:101175
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0045165	cell fate commitment	IGI	J:98303
Biological Process	GO:0090134	cell migration involved in mesendoderm migration	IMP	J:56519
Biological Process	GO:0090134	cell migration involved in mesendoderm migration	IMP	J:56519
Biological Process	GO:0090134	cell migration involved in mesendoderm migration	IMP	J:56519
Biological Process	GO:0090134	cell migration involved in mesendoderm migration	IMP	J:56519
Biological Process	GO:0008283	cell population proliferation	IMP	J:109474
Biological Process	GO:0008283	cell population proliferation	IMP	J:109474
Biological Process	GO:0008283	cell population proliferation	IMP	J:109474
Biological Process	GO:0008283	cell population proliferation	IGI	J:102854
Biological Process	GO:0021846	cell proliferation in forebrain	IMP	J:108506
Biological Process	GO:0021846	cell proliferation in forebrain	IMP	J:108506
Biological Process	GO:0021954	central nervous system neuron development	ISO	J:155856
Biological Process	GO:0060128	corticotropin hormone secreting cell differentiation	IDA	J:46975
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:56374
Biological Process	GO:0071542	dopaminergic neuron differentiation	TAS	J:227390
Biological Process	GO:0071542	dopaminergic neuron differentiation	ISO	J:164563
Biological Process	GO:0033563	dorsal/ventral axon guidance	ISO	J:155856
Biological Process	GO:0009953	dorsal/ventral pattern formation	IBA	J:265628
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	IMP	J:87304
Biological Process	GO:0035050	embryonic heart tube development	IBA	J:265628
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:109475
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IGI	J:102854
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	IGI	J:235627
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	IMP	J:152574
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	IDA	J:172023
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IBA	J:265628
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IDA	J:56088
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IMP	J:102854
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	IDA	J:46380
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	ISO	J:73065
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	IMP	J:108506
Biological Process	GO:0021798	forebrain dorsal/ventral pattern formation	IMP	J:108506
Biological Process	GO:0048853	forebrain morphogenesis	IMP	J:108506
Biological Process	GO:0021884	forebrain neuron development	ISO	J:155856
Biological Process	GO:0048699	generation of neurons	IMP	J:103123
Biological Process	GO:0008406	gonad development	ISO	J:164563
Biological Process	GO:0007507	heart development	IMP	J:109474
Biological Process	GO:0007507	heart development	IMP	J:109475
Biological Process	GO:0007507	heart development	IMP	J:109474
Biological Process	GO:0001947	heart looping	IMP	J:56374
Biological Process	GO:0003007	heart morphogenesis	IBA	J:265628
Biological Process	GO:0003007	heart morphogenesis	IMP	J:110620
Biological Process	GO:0042472	inner ear morphogenesis	IGI	J:98303
Biological Process	GO:0001822	kidney development	IMP	J:101175
Biological Process	GO:0120223	larynx morphogenesis	IGI	J:241145
Biological Process	GO:0035108	limb morphogenesis	IBA	J:265628
Biological Process	GO:0035108	limb morphogenesis	IGI	J:93163
Biological Process	GO:0030324	lung development	IMP	J:56374
Biological Process	GO:0060425	lung morphogenesis	IMP	J:56374
Biological Process	GO:0030539	male genitalia development	IDA	J:83431
Biological Process	GO:0000165	MAPK cascade	IMP	J:109474
Biological Process	GO:0008078	mesodermal cell migration	IMP	J:56519
Biological Process	GO:0008078	mesodermal cell migration	IMP	J:56519
Biological Process	GO:0008078	mesodermal cell migration	IMP	J:56519
Biological Process	GO:0030917	midbrain-hindbrain boundary development	IMP	J:124118
Biological Process	GO:0140014	mitotic nuclear division	IDA	J:83431
Biological Process	GO:0140014	mitotic nuclear division	IDA	J:83431
Biological Process	GO:0008045	motor neuron axon guidance	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:108506
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:108506
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:108506
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:102854
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:109474
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:108506
Biological Process	GO:0055026	negative regulation of cardiac muscle tissue development	ISO	J:164563
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:102854
Biological Process	GO:0001839	neural plate morphogenesis	IMP	J:108506
Biological Process	GO:0060563	neuroepithelial cell differentiation	ISO	J:164563
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:102854
Biological Process	GO:0030182	neuron differentiation	IBA	J:265628
Biological Process	GO:0035265	organ growth	IMP	J:149463
Biological Process	GO:0035265	organ growth	IGI	J:149463
Biological Process	GO:0001759	organ induction	IGI	J:96329
Biological Process	GO:0030916	otic vesicle formation	TAS	J:184501
Biological Process	GO:0030916	otic vesicle formation	IGI	J:124118
Biological Process	GO:0003151	outflow tract morphogenesis	IGI	J:172023
Biological Process	GO:0003151	outflow tract morphogenesis	IGI	J:172023
Biological Process	GO:0003151	outflow tract morphogenesis	IGI	J:172023
Biological Process	GO:0003148	outflow tract septum morphogenesis	IGI	J:175333
Biological Process	GO:0021543	pallium development	IMP	J:108506
Biological Process	GO:0021543	pallium development	IMP	J:108506
Biological Process	GO:0060037	pharyngeal system development	IGI	J:172023
Biological Process	GO:0060037	pharyngeal system development	IGI	J:172023
Biological Process	GO:0060037	pharyngeal system development	IGI	J:172023
Biological Process	GO:0051781	positive regulation of cell division	IEA	J:60000
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:56088
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:109474
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:46975
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IGI	J:205567
Biological Process	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	IDA	J:149152
Biological Process	GO:0010628	positive regulation of gene expression	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:51126
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:51126
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:51126
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:51126
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:56374
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:41974
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	IDA	J:83431
Biological Process	GO:0046622	positive regulation of organ growth	IGI	J:149463
Biological Process	GO:0046622	positive regulation of organ growth	IMP	J:149463
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IMP	J:105263
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IBA	J:265628
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IGI	J:102854
Biological Process	GO:0030334	regulation of cell migration	IBA	J:265628
Biological Process	GO:0042487	regulation of odontogenesis of dentin-containing tooth	IGI	J:41974
Biological Process	GO:0042487	regulation of odontogenesis of dentin-containing tooth	IGI	J:41974
Biological Process	GO:0006979	response to oxidative stress	ISO	J:155856
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	IDA	J:155850
Biological Process	GO:0072089	stem cell proliferation	IGI	J:102854
Biological Process	GO:0021544	subpallium development	IMP	J:108506
Biological Process	GO:0021544	subpallium development	IMP	J:108506
Biological Process	GO:0021537	telencephalon development	IMP	J:108506
Biological Process	GO:0021537	telencephalon development	IMP	J:108506
Biological Process	GO:0030878	thyroid gland development	IGI	J:149463
Biological Process	GO:0030878	thyroid gland development	IMP	J:149463
Biological Process	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation	IDA	J:46975

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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