Zap70 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Zap70
zeta-chain (TCR) associated protein kinase
MGI:99613

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IDA	J:35411
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0001784	phosphotyrosine residue binding	IPI	J:18500
Molecular Function	GO:0001784	phosphotyrosine residue binding	IPI	J:18500
Molecular Function	GO:0001784	phosphotyrosine residue binding	IPI	J:18500
Molecular Function	GO:0005515	protein binding	IPI	J:204615
Molecular Function	GO:0005515	protein binding	IPI	J:209882
Molecular Function	GO:0005515	protein binding	IPI	J:113565
Molecular Function	GO:0005515	protein binding	IPI	J:96052
Molecular Function	GO:0005515	protein binding	IPI	J:96052
Molecular Function	GO:0005515	protein binding	IPI	J:112392
Molecular Function	GO:0005515	protein binding	IPI	J:35635
Molecular Function	GO:0004672	protein kinase activity	IDA	J:89761
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:35411
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:40949
Molecular Function	GO:0004713	protein tyrosine kinase activity	IMP	J:41170
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:205441
Cellular Component	GO:0005737	cytoplasm	IDA	J:113565
Cellular Component	GO:0005829	cytosol	IDA	J:94701
Cellular Component	GO:0005829	cytosol	IDA	J:41090
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	IBA	J:265628
Cellular Component	GO:0001772	immunological synapse	IDA	J:113565
Cellular Component	GO:0016020	membrane	IDA	J:94701
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:113565
Cellular Component	GO:0042101	T cell receptor complex	ISO	J:18037
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0046632	alpha-beta T cell differentiation	IMP	J:27768
Biological Process	GO:0046632	alpha-beta T cell differentiation	IMP	J:41170
Biological Process	GO:0046632	alpha-beta T cell differentiation	IGI	J:42818
Biological Process	GO:0043366	beta selection	IGI	J:42818
Biological Process	GO:0019722	calcium-mediated signaling	IMP	J:41170
Biological Process	GO:0019722	calcium-mediated signaling	IMP	J:27768
Biological Process	GO:0019722	calcium-mediated signaling	IMP	J:27768
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0006955	immune response	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0035556	intracellular signal transduction	IMP	J:27768
Biological Process	GO:0045060	negative thymic T cell selection	IMP	J:27768
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:189787
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IMP	J:41170
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:200103
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:35411
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	IMP	J:27768
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	IGI	J:42818
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	IMP	J:27768
Biological Process	GO:0046638	positive regulation of alpha-beta T cell differentiation	IMP	J:41170
Biological Process	GO:0046641	positive regulation of alpha-beta T cell proliferation	IGI	J:42818
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	IMP	J:27768
Biological Process	GO:0050850	positive regulation of calcium-mediated signaling	IMP	J:41170
Biological Process	GO:0045582	positive regulation of T cell differentiation	IMP	J:41170
Biological Process	GO:0045582	positive regulation of T cell differentiation	IMP	J:41170
Biological Process	GO:0045582	positive regulation of T cell differentiation	ISO	J:73065
Biological Process	GO:0045059	positive thymic T cell selection	IMP	J:27768
Biological Process	GO:0045059	positive thymic T cell selection	ISO	J:73065
Biological Process	GO:0046777	protein autophosphorylation	IMP	J:41170
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:35411
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:40949
Biological Process	GO:0030217	T cell differentiation	IMP	J:41170
Biological Process	GO:0030217	T cell differentiation	IMP	J:41170
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:41170
Biological Process	GO:0045061	thymic T cell selection	IMP	J:41170
Biological Process	GO:0045061	thymic T cell selection	IMP	J:41170
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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