GO Annotations Graph

• Symbol: Dmtn
• Name: dematin actin binding protein
• ID: MGI:99670

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0043621	protein self-association	ISO	J:164563
Molecular Function	GO:0043621	protein self-association	IDA	J:76575
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0030507	spectrin binding	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	IBA	J:265628
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031253	cell projection membrane	IDA	J:137913
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:138919
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:137913
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:138919
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:137913
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0031095	platelet dense tubular network membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	IDA	J:187362
Cellular Component	GO:0014731	spectrin-associated cytoskeleton	ISO	J:164563
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:76575
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0051017	actin filament bundle assembly	IBA	J:265628
Biological Process	GO:0051693	actin filament capping	IEA	J:60000
Biological Process	GO:0090527	actin filament reorganization	IMP	J:192631
Biological Process	GO:0035585	calcium-mediated signaling using extracellular calcium source	IMP	J:192631
Biological Process	GO:0035584	calcium-mediated signaling using intracellular calcium source	IMP	J:192631
Biological Process	GO:0071277	cellular response to calcium ion	IMP	J:192631
Biological Process	GO:0071320	cellular response to cAMP	ISO	J:164563
Biological Process	GO:0007010	cytoskeleton organization	IEA	J:72247
Biological Process	GO:0048821	erythrocyte development	IMP	J:76575
Biological Process	GO:0030032	lamellipodium assembly	IBA	J:265628
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	IMP	J:137913
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	IMP	J:137913
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	IMP	J:137913
Biological Process	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	IMP	J:137913
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	IMP	J:137913
Biological Process	GO:0090315	negative regulation of protein targeting to membrane	IMP	J:137913
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	IMP	J:137913
Biological Process	GO:0030194	positive regulation of blood coagulation	IMP	J:192631
Biological Process	GO:0010763	positive regulation of fibroblast migration	IDA	J:137913
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	IMP	J:192631
Biological Process	GO:1901731	positive regulation of platelet aggregation	IMP	J:192631
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	IMP	J:192631
Biological Process	GO:0090303	positive regulation of wound healing	IMP	J:137913
Biological Process	GO:0070560	protein secretion by platelet	IMP	J:192631
Biological Process	GO:0065003	protein-containing complex assembly	IDA	J:76575
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IMP	J:76575
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IDA	J:137913
Biological Process	GO:0051489	regulation of filopodium assembly	ISO	J:164563
Biological Process	GO:0010591	regulation of lamellipodium assembly	ISO	J:164563