GO Annotations Graph

• Symbol: Rasgrf1
• Name: RAS protein-specific guanine nucleotide-releasing factor 1
• ID: MGI:99694

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035254	glutamate receptor binding	IPI	J:119025
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:245706
Molecular Function	GO:0005515	protein binding	IPI	J:245707
Molecular Function	GO:0005515	protein binding	IPI	J:198662
Molecular Function	GO:0005515	protein binding	IPI	J:120301
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:155856
Molecular Function	GO:0031267	small GTPase binding	ISO	J:155856
Cellular Component	GO:0097440	apical dendrite	ISO	J:155856
Cellular Component	GO:0016327	apicolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IDA	J:120301
Cellular Component	GO:0030426	growth cone	IDA	J:120301
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:155856
Biological Process	GO:0090630	activation of GTPase activity	IDA	J:120301
Biological Process	GO:0035556	intracellular signal transduction	IEA	J:72247
Biological Process	GO:0031175	neuron projection development	IDA	J:120301
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	IDA	J:120301
Biological Process	GO:0043547	positive regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	ISO	J:155856
Biological Process	GO:0007265	Ras protein signal transduction	IBA	J:265628
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	IMP	J:73863
Biological Process	GO:2000310	regulation of NMDA receptor activity	IGI	J:90111
Biological Process	GO:0035020	regulation of Rac protein signal transduction	IDA	J:120301
Biological Process	GO:0046578	regulation of Ras protein signal transduction	IDA	J:120301
Biological Process	GO:0035023	regulation of Rho protein signal transduction	IEA	J:72247
Biological Process	GO:0048167	regulation of synaptic plasticity	ISO	J:155856
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0007264	small GTPase mediated signal transduction	IEA	J:72247
Biological Process	GO:0044342	type B pancreatic cell proliferation	IMP	J:83950