Chrna7 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
MGI:99779

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042166	acetylcholine binding	ISO	J:155856
Molecular Function	GO:0042166	acetylcholine binding	ISO	J:164563
Molecular Function	GO:0042166	acetylcholine binding	IBA	J:265628
Molecular Function	GO:0015464	acetylcholine receptor activity	ISO	J:164563
Molecular Function	GO:0015464	acetylcholine receptor activity	IBA	J:265628
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	ISO	J:155856
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IBA	J:265628
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IDA	J:46773
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	ISO	J:73065
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IDA	J:46773
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:44288
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:74703
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:74703
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:74703
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	ISO	J:73065
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:74703
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IDA	J:46773
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IDA	J:46773
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:37665
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	ISO	J:73065
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:37665
Molecular Function	GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	IMP	J:37665
Molecular Function	GO:0008179	adenylate cyclase binding	ISO	J:155856
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:164563
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:0017081	chloride channel regulator activity	ISO	J:164563
Molecular Function	GO:0005230	extracellular ligand-gated monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005216	monoatomic ion channel activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:146775
Molecular Function	GO:0005515	protein binding	IPI	J:75439
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0015643	toxic substance binding	ISO	J:164563
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	ISO	J:155856
Cellular Component	GO:0005892	acetylcholine-gated channel complex	ISO	J:164563
Cellular Component	GO:0005892	acetylcholine-gated channel complex	ISO	J:155856
Cellular Component	GO:0005892	acetylcholine-gated channel complex	IPI	J:314378
Cellular Component	GO:0005892	acetylcholine-gated channel complex	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:101308
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:101308
Cellular Component	GO:0032279	asymmetric synapse	ISO	J:155856
Cellular Component	GO:0030673	axolemma	IDA	J:136701
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:263471
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:263471
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:263471
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:263471
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:103908
Cellular Component	GO:0098690	glycinergic synapse	ISO	J:155856
Cellular Component	GO:0030426	growth cone	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:74703
Cellular Component	GO:0016020	membrane	IDA	J:146775
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IEP	J:212011
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:212011
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:212011
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:263471
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:263471
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:263471
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:263471
Cellular Component	GO:0098793	presynapse	TAS	J:239203
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IEP	J:212011
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:212011
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:212011
Cellular Component	GO:0098897	spine apparatus membrane	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008306	associative learning	IMP	J:98842
Biological Process	GO:0008306	associative learning	IGI	J:94667
Biological Process	GO:0042113	B cell activation	IMP	J:112766
Biological Process	GO:0042113	B cell activation	IMP	J:103908
Biological Process	GO:0048149	behavioral response to ethanol	IMP	J:94231
Biological Process	GO:0035095	behavioral response to nicotine	IGI	J:121590
Biological Process	GO:0006816	calcium ion transport	ISO	J:73065
Biological Process	GO:0140059	dendrite arborization	IMP	J:196426
Biological Process	GO:0097061	dendritic spine organization	IMP	J:196426
Biological Process	GO:0006897	endocytosis	IMP	J:101438
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:44288
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:61536
Biological Process	GO:0030317	flagellated sperm motility	IMP	J:115434
Biological Process	GO:0060112	generation of ovulation cycle rhythm	IMP	J:92540
Biological Process	GO:0032611	interleukin-1 beta production	IMP	J:89610
Biological Process	GO:0032635	interleukin-6 production	IMP	J:89610
Biological Process	GO:0007611	learning or memory	IGI	J:157839
Biological Process	GO:0007611	learning or memory	ISO	J:155856
Biological Process	GO:0007611	learning or memory	IGI	J:151080
Biological Process	GO:0007611	learning or memory	IGI	J:239203
Biological Process	GO:0051899	membrane depolarization	ISO	J:155856
Biological Process	GO:0051899	membrane depolarization	IDA	J:314378
Biological Process	GO:0007613	memory	ISO	J:155856
Biological Process	GO:0007613	memory	IMP	J:123663
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IGI	J:238454
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	IGI	J:168638
Biological Process	GO:0098815	modulation of excitatory postsynaptic potential	IDA	J:168638
Biological Process	GO:0034220	monoatomic ion transmembrane transport	ISO	J:155856
Biological Process	GO:0034220	monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006811	monoatomic ion transport	IMP	J:61536
Biological Process	GO:0006811	monoatomic ion transport	IMP	J:44288
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:124406
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	IMP	J:89610
Biological Process	GO:0032715	negative regulation of interleukin-6 production	IMP	J:89610
Biological Process	GO:0001933	negative regulation of protein phosphorylation	IDA	J:148203
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IMP	J:124406
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IMP	J:89610
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:73065
Biological Process	GO:0050877	nervous system process	IBA	J:265628
Biological Process	GO:0019228	neuronal action potential	ISO	J:155856
Biological Process	GO:0042698	ovulation cycle	IMP	J:92450
Biological Process	GO:1905923	positive regulation of acetylcholine biosynthetic process	IC	J:157839
Biological Process	GO:1902004	positive regulation of amyloid-beta formation	IGI	J:157839
Biological Process	GO:1905920	positive regulation of CoA-transferase activity	IGI	J:157839
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IDA	J:238460
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IGI	J:157839
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:239214
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IGI	J:239203
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:155856
Biological Process	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	IMP	J:96657
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IGI	J:239203
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IGI	J:168638
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IDA	J:168638
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IMP	J:148203
Biological Process	GO:0051247	positive regulation of protein metabolic process	IGI	J:157839
Biological Process	GO:0051247	positive regulation of protein metabolic process	IGI	J:157839
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IDA	J:238460
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:1905906	regulation of amyloid fibril formation	IGI	J:157839
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:89610
Biological Process	GO:0042391	regulation of membrane potential	IBA	J:265628
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:44288
Biological Process	GO:0042391	regulation of membrane potential	ISO	J:73065
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:61536
Biological Process	GO:1901214	regulation of neuron death	IGI	J:157839
Biological Process	GO:0014061	regulation of norepinephrine secretion	IMP	J:96657
Biological Process	GO:2001023	regulation of response to drug	ISO	J:155856
Biological Process	GO:0051823	regulation of synapse structural plasticity	IC	J:157839
Biological Process	GO:0032222	regulation of synaptic transmission, cholinergic	IC	J:157839
Biological Process	GO:0032225	regulation of synaptic transmission, dopaminergic	IMP	J:122939
Biological Process	GO:1905144	response to acetylcholine	ISO	J:155856
Biological Process	GO:1904645	response to amyloid-beta	IMP	J:239203
Biological Process	GO:0009409	response to cold	IDA	J:148203
Biological Process	GO:0045471	response to ethanol	IMP	J:104831
Biological Process	GO:0032094	response to food	IMP	J:98842
Biological Process	GO:0035094	response to nicotine	ISO	J:155856
Biological Process	GO:0035094	response to nicotine	IGI	J:239214
Biological Process	GO:0035094	response to nicotine	IMP	J:46773
Biological Process	GO:0035094	response to nicotine	IMP	J:121645
Biological Process	GO:0050893	sensory processing	ISO	J:155856
Biological Process	GO:0050893	sensory processing	IDA	J:238460
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0050808	synapse organization	IGI	J:151080
Biological Process	GO:0007271	synaptic transmission, cholinergic	ISO	J:155856
Biological Process	GO:0007271	synaptic transmission, cholinergic	IBA	J:265628
Biological Process	GO:0007271	synaptic transmission, cholinergic	IMP	J:44288
Biological Process	GO:0042110	T cell activation	IMP	J:112766
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:89610
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:124406
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:89610
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:89610

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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