GO Annotations Graph

• Symbol: Slc7a2
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
• ID: MGI:99828

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015171	amino acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	IDA	J:40643
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	IMP	J:82914
Molecular Function	GO:0061459	L-arginine transmembrane transporter activity	IMP	J:69414
Molecular Function	GO:0015189	L-lysine transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0000064	L-ornithine transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:18492
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0089718	amino acid import across plasma membrane	ISO	J:164563
Biological Process	GO:0006865	amino acid transport	IEA	J:72247
Biological Process	GO:0006865	amino acid transport	IEA	J:60000
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:69414
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:82914
Biological Process	GO:1902475	L-alpha-amino acid transmembrane transport	ISO	J:164563
Biological Process	GO:0015807	L-amino acid transport	ISO	J:164563
Biological Process	GO:0097638	L-arginine import across plasma membrane	ISO	J:164563
Biological Process	GO:0097638	L-arginine import across plasma membrane	IBA	J:265628
Biological Process	GO:1903826	L-arginine transmembrane transport	ISO	J:164563
Biological Process	GO:1903826	L-arginine transmembrane transport	IDA	J:40643
Biological Process	GO:1903826	L-arginine transmembrane transport	ISO	J:155856
Biological Process	GO:1903826	L-arginine transmembrane transport	IMP	J:69414
Biological Process	GO:1903826	L-arginine transmembrane transport	IMP	J:82914
Biological Process	GO:1903352	L-ornithine transmembrane transport	IBA	J:265628
Biological Process	GO:0042116	macrophage activation	IMP	J:115060
Biological Process	GO:0006809	nitric oxide biosynthetic process	IMP	J:82914
Biological Process	GO:0002537	nitric oxide production involved in inflammatory response	IMP	J:114692
Biological Process	GO:0002537	nitric oxide production involved in inflammatory response	IMP	J:69414
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:114692
Biological Process	GO:0043030	regulation of macrophage activation	IMP	J:131710
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247