GO Annotations Graph

• Symbol: Cbfb
• Name: core binding factor beta
• ID: MGI:99851

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:70002
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:131081
Molecular Function	GO:0043565	sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Cellular Component	GO:0016513	core-binding factor complex	TAS	J:131081
Cellular Component	GO:0016513	core-binding factor complex	IBA	J:265628
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8865408
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8939880
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8940989
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8949284
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8955743
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8955833
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9008370
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9016554
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-8865513
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-8865525
Cellular Component	GO:0005634	nucleus	IDA	J:80669
Cellular Component	GO:0032991	protein-containing complex	ISO	J:11868
Biological Process	GO:0048469	cell maturation	IMP	J:80669
Biological Process	GO:0060216	definitive hemopoiesis	IMP	J:40963
Biological Process	GO:0030098	lymphocyte differentiation	IMP	J:80670
Biological Process	GO:0030099	myeloid cell differentiation	IMP	J:80670
Biological Process	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	IMP	J:131081
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:131081
Biological Process	GO:0001503	ossification	IMP	J:80669
Biological Process	GO:0001503	ossification	IMP	J:80670
Biological Process	GO:0001649	osteoblast differentiation	IMP	J:80669
Biological Process	GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	IMP	J:131081
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:80669
Biological Process	GO:0000209	protein polyubiquitination	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628