GO Annotations Graph

• Symbol: Hnrnpk
• Name: heterogeneous nuclear ribonucleoprotein K
• ID: MGI:99894

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042805	actinin binding	ISO	J:155856
Molecular Function	GO:0051117	ATPase binding	ISO	J:155856
Molecular Function	GO:1990829	C-rich single-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003690	double-stranded DNA binding	ISO	J:155856
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005521	lamin binding	ISO	J:155856
Molecular Function	GO:0003730	mRNA 3'-UTR binding	ISO	J:155856
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:1990715	mRNA CDS binding	ISO	J:155856
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0030628	pre-mRNA 3'-splice site binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:190257
Molecular Function	GO:0005515	protein binding	IPI	J:41036
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0043021	ribonucleoprotein complex binding	ISO	J:155856
Molecular Function	GO:0003723	RNA binding	IDA	J:167935
Molecular Function	GO:0003723	RNA binding	IDA	J:161520
Molecular Function	GO:0003697	single-stranded DNA binding	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0071013	catalytic step 2 spliceosome	ISO	J:164563
Cellular Component	GO:0005938	cell cortex	ISO	J:155856
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0010494	cytoplasmic stress granule	IDA	J:259116
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0098794	postsynapse	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:155856
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0005681	spliceosomal complex	IEA	J:60000
Biological Process	GO:1904322	cellular response to forskolin	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:155856
Biological Process	GO:0021987	cerebral cortex development	ISO	J:155856
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:73065
Biological Process	GO:2000173	negative regulation of branching morphogenesis of a nerve	ISO	J:155856
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:155856
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	IMP	J:204486
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0001541	ovarian follicle development	ISO	J:155856
Biological Process	GO:1903861	positive regulation of dendrite extension	ISO	J:155856
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:1905599	positive regulation of low-density lipoprotein receptor activity	ISO	J:164563
Biological Process	GO:0031643	positive regulation of myelination	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	ISO	J:155856
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	ISO	J:164563
Biological Process	GO:0033120	positive regulation of RNA splicing	ISO	J:155856
Biological Process	GO:0090129	positive regulation of synapse maturation	ISO	J:155856
Biological Process	GO:0050806	positive regulation of synaptic transmission	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:212291
Biological Process	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IMP	J:167935
Biological Process	GO:0010988	regulation of low-density lipoprotein particle clearance	ISO	J:164563
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	IBA	J:265628
Biological Process	GO:0099175	regulation of postsynapse organization	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006396	RNA processing	IEA	J:72247
Biological Process	GO:0008380	RNA splicing	IEA	J:60000