Lama2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Lama2
laminin, alpha 2
MGI:99912

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005201	extracellular matrix structural constituent	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:213615
Molecular Function	GO:0005102	signaling receptor binding	IEA	J:72247
Cellular Component	GO:0005604	basement membrane	ISO	J:155856
Cellular Component	GO:0005604	basement membrane	ISO	J:164563
Cellular Component	GO:0005604	basement membrane	NAS	J:320094
Cellular Component	GO:0005604	basement membrane	IBA	J:265628
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:42107
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0005604	basement membrane	IDA	J:77264
Cellular Component	GO:0005604	basement membrane	IDA	J:44761
Cellular Component	GO:0005604	basement membrane	IDA	J:46802
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426496
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426528
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426626
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2447193
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8878599
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-9619682
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426616
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2467092
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:44761
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:44761
Cellular Component	GO:0098637	protein complex involved in cell-matrix adhesion	NAS	J:320095
Cellular Component	GO:0042383	sarcolemma	IDA	J:66558
Cellular Component	GO:0042383	sarcolemma	IDA	J:46802
Cellular Component	GO:0043083	synaptic cleft	IDA	J:44761
Cellular Component	GO:0043083	synaptic cleft	IDA	J:44761
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IGI	J:150519
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0045785	positive regulation of cell adhesion	NAS	J:320337
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	NAS	J:207441
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	NAS	J:320093
Biological Process	GO:0032224	positive regulation of synaptic transmission, cholinergic	IMP	J:29768
Biological Process	GO:0110011	regulation of basement membrane organization	NAS	J:320696
Biological Process	GO:0030155	regulation of cell adhesion	IEA	J:72247
Biological Process	GO:0030334	regulation of cell migration	IEA	J:72247
Biological Process	GO:0045995	regulation of embryonic development	IEA	J:72247

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24