GO Annotations Graph

• Symbol: Lamc2
• Name: laminin, gamma 2
• ID: MGI:99913

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0008201	heparin binding	IDA	J:73852
Molecular Function	GO:0005515	protein binding	IPI	J:73852
Molecular Function	GO:0005515	protein binding	IPI	J:73852
Cellular Component	GO:0005604	basement membrane	IDA	J:42107
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:139122
Cellular Component	GO:0005604	basement membrane	IDA	J:73852
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005604	basement membrane	IDA	J:98797
Cellular Component	GO:0005938	cell cortex	ISO	J:155856
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0031012	extracellular matrix	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426626
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2533953
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8878599
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426616
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005607	laminin-2 complex	ISO	J:155856
Cellular Component	GO:0005610	laminin-5 complex	IDA	J:42107
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IBA	J:265628