GO Annotations Graph

• Symbol: Lamb2
• Name: laminin, beta 2
• ID: MGI:99916

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265604
Molecular Function	GO:0005201	extracellular matrix structural constituent	RCA	J:265607
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0005178	integrin binding	IPI	J:163713
Molecular Function	GO:0005178	integrin binding	IPI	J:163713
Molecular Function	GO:0005178	integrin binding	IPI	J:163713
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IDA	J:123242
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IMP	J:123242
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IDA	J:123242
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IEP	J:123242
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IDA	J:123242
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IDA	J:123242
Molecular Function	GO:0150043	structural constituent of synapse-associated extracellular matrix	IDA	J:123242
Cellular Component	GO:0005604	basement membrane	NAS	J:320094
Cellular Component	GO:0005604	basement membrane	ISO	J:164563
Cellular Component	GO:0005604	basement membrane	IDA	J:132545
Cellular Component	GO:0005604	basement membrane	IDA	J:27732
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265604
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426496
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426528
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2426626
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-2447193
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-8878599
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2426616
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-NUL-2467092
Cellular Component	GO:0043256	laminin complex	IBA	J:265628
Cellular Component	GO:0043256	laminin complex	IDA	J:19321
Cellular Component	GO:0005608	laminin-3 complex	ISO	J:164563
Cellular Component	GO:0005608	laminin-3 complex	IDA	J:163713
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:44761
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:44761
Cellular Component	GO:0098637	protein complex involved in cell-matrix adhesion	NAS	J:320095
Cellular Component	GO:0045202	synapse	IDA	J:123242
Cellular Component	GO:0043083	synaptic cleft	IDA	J:44761
Cellular Component	GO:0043083	synaptic cleft	IDA	J:44761
Biological Process	GO:0014002	astrocyte development	IGI	J:160410
Biological Process	GO:0048677	axon extension involved in regeneration	IMP	J:44761
Biological Process	GO:0007411	axon guidance	IGI	J:150519
Biological Process	GO:0070831	basement membrane assembly	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	IGI	J:160410
Biological Process	GO:0072274	metanephric glomerular basement membrane development	IMP	J:27732
Biological Process	GO:0072274	metanephric glomerular basement membrane development	IMP	J:113125
Biological Process	GO:0072249	metanephric podocyte development	IMP	J:113125
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:23783
Biological Process	GO:0007528	neuromuscular junction development	IMP	J:126496
Biological Process	GO:0031175	neuron projection development	IDA	J:163713
Biological Process	GO:0045785	positive regulation of cell adhesion	NAS	J:320337
Biological Process	GO:2001046	positive regulation of integrin-mediated signaling pathway	NAS	J:207441
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	NAS	J:320093
Biological Process	GO:0110011	regulation of basement membrane organization	NAS	J:320696
Biological Process	GO:0060041	retina development in camera-type eye	IGI	J:160410
Biological Process	GO:0014044	Schwann cell development	IDA	J:167200
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IBA	J:265628
Biological Process	GO:0050808	synapse organization	IMP	J:123242
Biological Process	GO:0050808	synapse organization	IMP	J:123242
Biological Process	GO:0007601	visual perception	IGI	J:160410