Hmga2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hmga2
high mobility group AT-hook 2
MGI:101761

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm9(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ Hmga2^tm1.1Mmw/Hmga2⁺ Kras^tm4Tyj/Kras⁺ Tg(Pdx1-cre)6Tuv/0 Trp53^tm2Tyj/Trp53⁺ involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * FVB/N	increased metastatic potential	J:245611
	increased pancreatic ductal adenocarcinoma incidence	J:245611
Hmga2^pg-Tg40ACha/Hmga2⁺ involves: C57BL/6J * CBA/J	abnormal brain size	J:21153
	decreased body weight	J:21153
	small adrenal glands	J:21153
	small testis	J:21153
Hmga2^pg-Tg40ACha/Hmga2^pg-Tg40ACha involves: C57BL/6J * CBA/J	abnormal brain size	J:21153
	decreased body size	J:10325
	decreased body weight	J:21153
	proportional dwarf	J:21153
	small adrenal glands	J:21153
	small testis	J:21153
Hmga2^pg-Tg40ACha/Hmga2^pg-Tg40BCha involves: C57BL/6J * CBA/J	decreased body size	J:10325
	decreased body weight	J:21153
	proportional dwarf	J:21153
Hmga2^tm1Cha/Hmga2⁺ Lep^ob/Lep^ob involves: 129S7/SvEvBrd * C57BL/6J	decreased body size	J:61493
	decreased body weight	J:61493
Hmga2^tm1Cha/Hmga2^tm1Cha Lep^ob/Lep^ob involves: 129S7/SvEvBrd * C57BL/6J	abnormal body weight	J:61493
	abnormal fat pad morphology	J:61493
	decreased body size	J:61493
	decreased inguinal fat pad weight	J:61493
	decreased mesenteric fat pad weight	J:61493

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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