Cfl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cfl2
cofilin 2, muscle
MGI:101763

19 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cfl2^tm1.1Itl/Cfl2^tm1.1Itl involves: C57BL/6J * C57BL/6NTac	abnormal food intake	J:182571
	abnormal locomotor activation	J:182571
	abnormal sarcomere morphology	J:182571
	abnormal skeletal muscle fiber morphology	J:182571
	abnormal skeletal muscle fiber type ratio	J:182571
	abnormal skeletal muscle morphology	J:182571
	abnormal suckling behavior	J:182571
	decreased body length	J:182571
	decreased body size	J:182571
	decreased body weight	J:182571
	impaired righting response	J:182571
	muscle weakness	J:182571
	normal nervous system phenotype	J:182571
	postnatal growth retardation	J:182571
	postnatal lethality, complete penetrance	J:182571
	skeletal muscle fiber degeneration	J:182571
Cfl2^tm1Itl/Cfl2^tm1Itl Tg(ACTA1-cre)79Jme/0 involves: C57BL/6J * C57BL/6NTac * SJL	abnormal sarcomere morphology	J:182571
	abnormal skeletal muscle fiber morphology	J:182571
	abnormal skeletal muscle morphology	J:182571
	postnatal lethality, complete penetrance	J:182571
Cfl2^tm1Itl/Cfl2^tm1Itl Tg(Ckmm-cre)5Khn/0 involves: C57BL/6 * C57BL/6NTac * FVB/N	abnormal skeletal muscle morphology	J:182571
	abnormal Z line morphology	J:182571
	decreased body size	J:182571
	decreased body weight	J:182571
	postnatal lethality, incomplete penetrance	J:182571
	premature death	J:182571
	skeletal muscle fiber degeneration	J:182571
Cfl2^tm1Itl/Cfl2^tm1Itl Tg(Mef2c-cre)1Blk/0 involves: C57BL/6NTac	abnormal skeletal muscle morphology	J:182571
	abnormal Z line morphology	J:182571
	postnatal lethality, complete penetrance	J:182571

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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