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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mcl1
myeloid cell leukemia sequence 1
MGI:101769
6 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bcl2l1tm1Ywh/Bcl2l1tm1Ywh
Mcl1tm1Ywh/Mcl1tm1Ywh
Tg(Cd4-cre)1Cwi/0
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		absent CD4-positive, alpha-beta T cells J:137400
absent CD8-positive, alpha-beta T cells J:137400
decreased double-positive T cell number J:137400
Mcl1tm1Yen/Mcl1tm1Yen
Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal double-positive T cell morphology J:146246
decreased CD8-positive, alpha-beta T cell number J:146246
Mcl1tm1Yen/Mcl1tm1Yen
Tg(TcraTcrb)425Cbn/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal double-positive T cell morphology J:146246
decreased CD4-positive, alpha-beta T cell number J:146246
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory