Cd79a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd79a
CD79A antigen (immunoglobulin-associated alpha)
MGI:101774

54 phenotypes from 17 alleles in 15 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^m1Anu/Cd79a^m1Anu C57BL/6-Cd79a^m1Anu	absent pre-B cells	J:171924
Cd79a^m1Anu/Cd79a^m1Anu involves: C57BL/6JSfdAnu * C57BL/10Sg * C57BR/cd	absent pre-B cells	J:104190
	decreased IgG level	J:104190
Cd79a^m1Btlr/Cd79a^m1Btlr involves: C57BL/6J	abnormal class switch recombination	J:185495
	decreased B cell number	J:185495
	decreased IgG level	J:185495
	decreased IgM level	J:185495
Cd79a^m1Btlr/Cd79a^m1Btlr involves: C57BL/6J * C57BL/10J	abnormal humoral immune response	J:174338
	decreased B cell number	J:174338
	decreased IgG level	J:174338
	decreased IgM level	J:174338
Cd79a^m2Btlr/Cd79a^m2Btlr C57BL/6J-Cd79a^m2Btlr	decreased B-1 B cell number	J:254836
	decreased IgM level	J:254836
	impaired humoral immune response	J:254836
Cd79a^{tm1(BAP31N-EGFP)Pld}/Cd79a^{tm1(BAP31N-EGFP)Pld} Not Specified	no abnormal phenotype detected	J:75114
Cd79a^tm1(cre)Reth/Cd79a⁺ involves: BALB/c * C57BL/6	no abnormal phenotype detected	J:113645
Cd79a^{tm1.1(BAP31N-EGFP)Pld}/Cd79a^{tm1.1(BAP31N-EGFP)Pld} Not Specified	abnormal immune system cell morphology	J:75114
Cd79a^tm1.1Cgn/Cd79a^tm1.1Cgn involves: 129P2/OlaHsd	decreased B-1a cell number	J:124400
Cd79a^tm1.1Cgn/Cd79a^tm1.1Cgn involves: 129P2/OlaHsd * C57BL/6	abnormal B cell activation	J:71100
	decreased B-1 B cell number	J:71100
	decreased IgG1 level	J:71100
	decreased marginal zone B cell number	J:71100
	decreased mature B cell number	J:71100
Cd79a^tm1.1Rsky/Cd79a^tm1.1Rsky involves: C57BL/6	abnormal humoral immune response	J:179254
	decreased IgG2b level	J:179254
	decreased IgG2c level	J:179254
	decreased IgG3 level	J:179254
	decreased marginal zone B cell number	J:179254
	decreased mature B cell number	J:179254
	normal hematopoietic system phenotype	J:179254
	normal immune system phenotype	J:179254
	increased anti-single stranded DNA antibody level	J:179254
	increased IgG2b level	J:179254
	increased IgG2c level	J:179254
	increased immature B cell number	J:179254
	increased pre-B cell number	J:179254
	increased transitional stage B cell number	J:179254
	increased transitional stage T1 B cell number	J:179254
	increased transitional stage T2 B cell number	J:179254
	increased transitional stage T3 B cell number	J:179254
Cd79a^tm2Cgn/Cd79a^tm2Cgn involves: C57BL/6	decreased mature B cell number	J:66840, J:71100
	decreased pre-B cell number	J:66840, J:71100
	increased pro-B cell number	J:66840
Cd79a^tm2Cgn/Cd79a^tm2Cgn involves: C57BL/6 * C.B-20	decreased B cell number	J:80885
	decreased immunoglobulin level	J:80885
	decreased mature B cell number	J:80885
Cd79a^tm2Pld/Cd79a^tm2Pld BALB/c-Cd79a^tm2Pld	abnormal B cell differentiation	J:87492
	abnormal T cell differentiation	J:87492
	absent mature B cells	J:87492
	decreased double-positive T cell number	J:87492
Cd79a^tm3Cgn/Cd79a^tm3Cgn Tg(Mx1-cre)1Cgn/? involves: C57BL/6 * CBA	abnormal metallophilic macrophage morphology	J:88620
	abnormal spleen marginal zone macrophage morphology	J:88620
	abnormal spleen red pulp morphology	J:88620
	decreased B cell number	J:88620
Cd79a^tm3Cgn/Cd79a^tm4.1Cgn involves: C57BL/6 * CBA	normal immune system phenotype	J:88620
Cd79a^tm4.1Cgn/Cd79a^tm4.1Cgn involves: C57BL/6	abnormal B cell differentiation	J:91091
Cd79a^tm4Cgn/Cd79a^tm4.1Cgn Tg(Cr2-cre)3Cgn/0 involves: 129P2/OlaHsd * C57BL/6	decreased B cell number	J:91091
	decreased IgD level	J:91091
	decreased IgM level	J:91091
Cd79a^tm4Cgn/Cd79a^tm4.1Cgn Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	absent immature B cells	J:91091
	arrested B cell differentiation	J:91091
	decreased B cell number	J:91091
	decreased follicular B cell number	J:91091
	decreased marginal zone B cell number	J:91091
Cd79a^tm5.1Cgn/Cd79a^tm5.1Cgn involves: 129 * C57BL/6	abnormal B cell morphology	J:125719
	decreased B-1a cell number	J:125719
	decreased immature B cell number	J:125719
	decreased mature B cell number	J:125719
	decreased pre-B cell number	J:125719
	decreased T cell number	J:125719
	increased pro-B cell number	J:125719
Cd79a^tm5.1Cgn/Cd79a^tm5.1Cgn involves: 129P2/OlaHsd * C57BL/6	abnormal B cell differentiation	J:91091
Cd79a^tm5Cgn/Cd79a^tm5.1Cgn Tg(Cr2-cre)3Cgn/0 involves: 129P2/OlaHsd * C57BL/6	decreased B cell number	J:91091
Cd79a^tm5Cgn/Cd79a^tm5.1Cgn Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	absent immature B cells	J:91091
	arrested B cell differentiation	J:91091
	decreased B cell number	J:91091
Cd79a^tm6Cgn/Cd79a^tm6Cgn involves: C57BL/6	abnormal B cell number	J:113407
	abnormal B cell physiology	J:113407
	abnormal cell cycle	J:113407
	abnormal humoral immune response	J:113407
	abnormal immunoglobulin level	J:113407
	abnormal mitosis	J:113407
	decreased B cell proliferation	J:113407
	decreased B-1a cell number	J:113407
	decreased IgG2a level	J:113407
	decreased IgG3 level	J:113407
	decreased IgM level	J:113407
	normal immune system phenotype	J:113407
	increased transitional stage B cell number	J:113407
Cd79a^tm7Cgn/Cd79a^tm7Cgn involves: C57BL/6	abnormal immune system physiology	J:113407

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