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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cd79a
CD79A antigen (immunoglobulin-associated alpha)
MGI:101774
128 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atmintm1.1Jhh/Atmintm1.1Jhh
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Cd79atm1(cre)Reth/Cd79a+
Tg(IghMyc)22Bri/0
B6.Cg-Bcl2l11tm1.1Ast Cd79atm1(Cre)Reth Atmintm1.1Jhh Tg(IghMyc)22Bri 		increased lymphoma incidence J:230105
Atmintm1.1Jhh/Atmintm1.1Jhh
Cd79atm1(cre)Reth/Cd79a+
B6.Cg-Cd79atm1(Cre)Reth Atmintm1.1Jhh 		decreased B cell number J:230105
decreased IgG1 level J:230105
decreased immature B cell number J:230105
increased B cell apoptosis J:230105
Atmintm1.1Jhh/Atmintm1.1Jhh
Cd79atm1(cre)Reth/Cd79a+
Tg(IghMyc)22Bri/0
B6.Cg-Cd79atm1(Cre)Reth Atmintm1.1Jhh Tg(IghMyc)22Bri 		decreased B cell number J:230105
decreased immature B cell number J:230105
decreased lymphoma incidence J:230105
increased B cell apoptosis J:230105
increased tumor latency J:230105
Atmintm1.2Jhh/Atmintm1.2Jhh
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Cd79atm1(cre)Reth/Cd79a+
involves: 129S1/Sv * BALB/c * C57BL/6 		enlarged spleen J:191832
normal immune system phenotype J:191832
increased B cell number J:191832
increased immature B cell number J:191832
increased pre-B cell number J:191832
increased spleen weight J:191832
Atmintm1.2Jhh/Atmintm1.2Jhh
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		abnormal B cell differentiation J:191832
abnormal B cell physiology J:191832
decreased immature B cell number J:191832
decreased mature B cell number J:191832
decreased pre-B cell number J:191832
decreased spleen weight J:191832
small spleen J:191832
Atmintm1.2Jhh/Atmintm1.2Jhh
Trp53tm1Brn/Trp53tm1Brn
Cd79atm1(cre)Reth/Cd79a+
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		decreased B cell number J:191832
decreased immature B cell number J:191832
Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Dicer1tm1Mmk/Dicer1tm1Mmk
Cd79atm1(cre)Reth/Cd79a+
involves: 129S1/Sv * BALB/c 		decreased B cell number J:135783
decreased mature B cell number J:135783
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 * C57BL/6JJcl 		abnormal humoral immune response J:190943
abnormal memory B cell morphology J:190943
abnormal memory B cell physiology J:190943
abnormal somatic hypermutation frequency J:190943
decreased germinal center B cell number J:190943
Bcl6tm1.1Mtto/Bcl6tm1.1Mtto
Cd79atm1(cre)Reth/Cd79a+
Tg(Cd4-cre)1Cwi/0
involves: BALB/c * C57BL/6 * C57BL/6JJcl * DBA/2 		decreased germinal center B cell number J:190943
normal immune system phenotype J:190943
Blnktm1Pjln/Blnktm1Pjln
Cd79atm1(cre)Reth/Cd79atm1(cre)Reth
Mzb1tm1.1Rug/Mzb1tm1.1Rug
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL 		abnormal bone marrow cell physiology J:211639
Cd79am1Anu/Cd79am1Anu
Rasgrp1m1Anu/Rasgrp1m1Anu
involves: C57BL/6JSfdAnu * CBA/J 		normal immune system phenotype J:207898
Cd79atm1(cre)Reth/Cd79a+
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
involves: 129X1/SvJ * BALB/c * C57BL/6 		abnormal enzyme/coenzyme activity J:113645
Cd79atm1(cre)Reth/Cd79a+
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(BCL2)22Wehi/0
involves: BALB/c * C57BL/6JWehi * SJL/JWehi 		decreased B cell number J:135783
decreased mature B cell number J:135783
Cd79atm1(cre)Reth/Cd79a+
Inpp5dtm1Rav/Inpp5dtm1Rav
involves: 129 * BALB/c * C57BL/6 		increased anti-chromatin antibody level J:178833
increased anti-double stranded DNA antibody level J:178833
increased anti-nuclear antigen antibody level J:178833
increased anti-single stranded DNA antibody level J:178833
increased autoantibody level J:178833
increased IgG level J:178833
increased susceptibility to systemic lupus erythematosus J:178833
premature death J:178833
Cd79atm1(cre)Reth/Cd79a+
Huwe1tm1.1Mak/Y
B6.Cg-Cd79atm1(cre)Reth Huwe1tm1.1Mak 		abnormal B cell differentiation J:181705
abnormal class switch recombination J:181705
abnormal humoral immune response J:181705
absent B-1a cells J:181705
decreased B cell proliferation J:181705
decreased follicular B cell number J:181705
decreased IgA level J:181705
decreased IgG1 level J:181705
decreased IgG2a level J:181705
decreased IgG3 level J:181705
decreased IgM level J:181705
decreased marginal zone B cell number J:181705
decreased mature B cell number J:181705
decreased pre-B cell number J:181705
decreased transitional stage B cell number J:181705
increased B cell apoptosis J:181705
increased susceptibility to Riboviria infection J:181705
Cd79atm1(cre)Reth/Cd79a+
Huwe1tm1.1Mak/Y
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * SJL 		abnormal class switch recombination J:181705
absent B-1a cells J:181705
decreased IgG1 level J:181705
decreased IgM level J:181705
normal immune system phenotype J:181705
Cd79atm1(cre)Reth/Cd79a+
Wastm1.1Ldn/Y
involves: BALB/c * C57BL/6 		abnormal B cell physiology J:182528
abnormal renal corpuscle morphology J:182528
decreased B cell number J:182528
decreased follicular B cell number J:182528
decreased marginal zone B cell number J:182528
decreased mature B cell number J:182528
increased anti-chromatin antibody level J:182528
increased anti-double stranded DNA antibody level J:182528
increased anti-single stranded DNA antibody level J:182528
increased autoantibody level J:182528
increased germinal center B cell number J:182528
increased IgM level J:182528
increased plasma cell number J:182528
Cd79atm1(cre)Reth/Cd79a+
Wastm1.1Ldn/Was+
involves: BALB/c * C57BL/6 		abnormal B cell number J:182528
abnormal B cell proliferation J:182528
Cd79atm1(cre)Reth/Cd79a+
Wastm1.1Ldn/Wastm1.1Ldn
involves: BALB/c * C57BL/6 		abnormal B cell physiology J:182528
abnormal renal corpuscle morphology J:182528
decreased B cell number J:182528
decreased follicular B cell number J:182528
decreased marginal zone B cell number J:182528
decreased mature B cell number J:182528
increased anti-chromatin antibody level J:182528
increased anti-double stranded DNA antibody level J:182528
increased anti-single stranded DNA antibody level J:182528
increased autoantibody level J:182528
increased germinal center B cell number J:182528
increased IgM level J:182528
increased plasma cell number J:182528
Cd79atm1(cre)Reth/Cd79a+
Nfkbiztm1.1Muta/Nfkbiztm1.1Muta
involves: BALB/c * C57BL/6 		normal immune system phenotype J:194832
Cd79atm1(cre)Reth/Cd79a+
Nr4a1tm1Pcn/Nr4a1tm1Pcn
involves: 129 * BALB/c 		increased B cell proliferation J:306652
Cd79atm1(cre)Reth/Cd79a+
Nr4a1tm1Pcn/Nr4a1tm1Pcn
Nr4a3em1Juz/Nr4a3em1Juz
involves: 129 * BALB/c * C57BL/6 		decreased B cell apoptosis J:306652
normal immune system phenotype J:306652
increased B cell proliferation J:306652
Cd79atm1(cre)Reth/Cd79a+
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL 		abnormal B cell differentiation J:209928
abnormal B cell number J:209928
decreased pre-B cell number J:209928
increased pro-B cell number J:209928
normal neoplasm J:209928
Cd79atm1(cre)Reth/Cd79a+
Slc39a10tm1.1Tfk/Slc39a10tm1.1Tfk
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J 		decreased B cell number J:213935
decreased IgA level J:213935
decreased IgE level J:213935
decreased IgG1 level J:213935
decreased IgG2b level J:213935
decreased IgG2c level J:213935
decreased IgG3 level J:213935
decreased IgM level J:213935
decreased immunoglobulin level J:213935
decreased pro-B cell number J:213935
spleen atrophy J:213935
Cd79atm1(cre)Reth/Cd79a+
Dynll1tm1.1Jhh/Dynll1tm1.1Jhh
B6.Cg-Dynll1tm1.1Jhh Cd79atm1(Cre)Reth 		abnormal B cell morphology J:230105
decreased immature B cell number J:230105
decreased mature B cell number J:230105
decreased pre-B cell number J:230105
Cd79atm1(cre)Reth/Cd79a+
Dynll1tm1.1Jhh/Dynll1tm1.1Jhh
Tg(IghMyc)22Bri/0
B6.Cg-Dynll1tm1.1Jhh Cd79atm1(Cre)Reth Tg(IghMyc)22Bri 		decreased immature B cell number J:230105
decreased lymphoma incidence J:230105
Cd79atm1(cre)Reth/Cd79a+
Ctnnbl1tm1.1Crad/Ctnnbl1tm1.1Crad
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL 		abnormal B cell proliferation J:232010
abnormal class switch recombination J:232010
decreased B cell proliferation J:232010
normal immune system phenotype J:232010
Cd79atm1(cre)Reth/Cd79a+
Orai1tm1Smua/Orai1tm1Smua
involves: BALB/c * C57BL/6J 		abnormal B cell activation J:345485
abnormal B cell physiology J:345485
abnormal calcium ion homeostasis J:345485
normal immune system phenotype J:345485
Cd79atm1(cre)Reth/Cd79a+
Orai1tm1Smua/Orai1tm1Smua
Orai3em1.1Treb/Orai3em1.1Treb
involves: BALB/c * C57BL/6J * C57BL/6N 		abnormal B cell activation J:345485
abnormal B cell physiology J:345485
abnormal calcium ion homeostasis J:345485
decreased B cell proliferation J:345485
normal immune system phenotype J:345485
Cd79atm1(cre)Reth/Cd79a+
Commd8tm1.1Ksuz/Commd8tm1.1Ksuz
involves: BALB/c * C57BL/6NSlc * SJL 		abnormal follicular B cell physiology J:278399
abnormal plasmablast number J:278399
abnormal spleen B cell follicle morphology J:278399
decreased follicular B cell number J:278399
decreased IgG1 level J:278399
decreased IgG2b level J:278399
decreased IgG2c level J:278399
decreased IgG3 level J:278399
decreased IgM level J:278399
decreased mature B cell number J:278399
decreased spleen germinal center number J:278399
normal immune system phenotype J:278399
Cd79atm1(cre)Reth/Cd79a+
Commd3tm1.1Ksuz/Commd3tm1.1Ksuz
involves: BALB/c * C57BL/6NSlc * SJL 		abnormal follicular B cell physiology J:278399
abnormal plasmablast number J:278399
abnormal spleen B cell follicle morphology J:278399
decreased follicular B cell number J:278399
decreased IgG1 level J:278399
decreased IgG2b level J:278399
decreased IgG2c level J:278399
decreased IgM level J:278399
decreased mature B cell number J:278399
decreased spleen germinal center number J:278399
normal immune system phenotype J:278399
Cd79atm1(cre)Reth/Cd79a+
Phf5atm1.1Oux/Phf5atm1.1Oux
involves: BALB/c * C57BL/6J 		abnormal B cell physiology J:345807
abnormal B cell receptor editing J:345807
abnormal immunoglobulin heavy chain V(D)J recombination J:345807
decreased B cell number J:345807
decreased early pro-B cell number J:345807
decreased immature B cell number J:345807
decreased late pro-B cell number J:345807
decreased mature B cell number J:345807
decreased pre-B cell number J:345807
increased pre-pro B cell number J:345807
small spleen J:345807
Cd79atm1(cre)Reth/Cd79a+
Phf5atm1.1Oux/Phf5atm1.1Oux
Tg(IghelMD4)4Ccg/0
involves: BALB/c * C57BL/6 * C57BL/6J 		abnormal B cell number J:345807
Cd79atm1(cre)Reth/Cd79a+
Orai3em1.1Treb/Orai3em1.1Treb
involves: BALB/c * C57BL/6J * C57BL/6N 		abnormal B cell activation J:345485
normal immune system phenotype J:345485
Cd79atm1(cre)Reth/Cd79a+
Eif4a1tm1.1Bea/Eif4a1tm1.1Bea
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		decreased B cell number J:344730
decreased pro-B cell number J:344730
Cd79atm1(cre)Reth/Cd79a+
Eif4btm1.1Tnr/Eif4btm1.1Tnr
Eif4htm1c(EUCOMM)Wtsi/Eif4htm1c(EUCOMM)Wtsi
involves: BALB/c * C57BL/6 * C57BL/6N 		decreased IgG1 level J:344730
decreased mature B cell number J:344730
normal hematopoietic system phenotype J:344730
Cd79atm1(cre)Reth/Cd79atm1(cre)Reth
Mzb1tm1.1Rug/Mzb1tm1.1Rug
involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL 		abnormal B cell number J:211639
decreased pre-B cell number J:211639
increased late pro-B cell number J:211639
increased pro-B cell number J:211639
small spleen J:211639
Cd79atm1.1Cgn/Cd79a+
Cd79btm1Gzmn/Cd79btm1Gzmn
involves: 129P2/OlaHsd 		decreased B cell number J:179254
decreased pre-B cell number J:179254
increased pro-B cell number J:179254
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm1Gzmn/Cd79b+
involves: 129P2/OlaHsd 		decreased B cell number J:179254
decreased pre-B cell number J:179254
increased pro-B cell number J:179254
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm1Gzmn/Cd79btm1Gzmn
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		abnormal B cell differentiation J:124400
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm1Gzmn/Cd79btm1Gzmn
involves: 129P2/OlaHsd 		abnormal B cell differentiation J:179254
absent pre-B cells J:179254
decreased B cell number J:179254
increased pro-B cell number J:179254
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm2.1Mnz/Cd79btm2.1Mnz
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		absent mature B cells J:71100
arrested B cell differentiation J:71100
Cd79atm1.1Cgn/Cd79atm1.1Cgn
Cd79btm3Mnz/Cd79btm3Mnz
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		normal immune system phenotype J:128768
Cd79atm2(cre/Esr1*)Reth/Cd79a+
Rag1tm1.1Sadu/Rag1tm1.1Sadu
involves: BALB/c 		arrested B cell differentiation J:155473
Cd79atm2(cre/Esr1*)Reth/Cd79a+
Rag1tm1.1Sadu/Rag1tm1.1Sadu
involves: BALB/c 		normal immune system phenotype J:155473
Cd79atm2Cgn/Cd79atm2Cgn
Cd79btm2.1Mnz/Cd79btm2.1Mnz
involves: 129/Sv * C57BL/6 		arrested B cell differentiation J:66840
decreased transitional stage B cell number J:66840
Cd79atm2Pld/Cd79atm2Pld
Cd79btm1Mnz/Cd79btm1Mnz
involves: 129S1/Sv * BALB/c 		absent pre-B cells J:87492
Cd79atm4.1Cgn/Cd79atm4.1Cgn
Ightm1.2Rsky/Igh+
involves: BALB/c * C57BL/6 		abnormal pro-B cell differentiation J:125719
Cd79atm5.1Cgn/Cd79a+
Ightm1.2Rsky/Igh+
involves: 129 * BALB/c * C57BL/6 		abnormal class switch recombination J:125719
Cd79atm5.1Cgn/Cd79atm5.1Cgn
Ightm1.2Rsky/Igh+
involves: 129 * BALB/c * C57BL/6 		abnormal class switch recombination J:125719
Cd79atm5.1Cgn/Cd79atm5.1Cgn
Ightm1.2Rsky/Ightm1.2Rsky
involves: 129 * BALB/c * C57BL/6 		abnormal B cell morphology J:125719
abnormal class switch recombination J:125719
decreased immature B cell number J:125719
decreased mature B cell number J:125719
decreased pre-B cell number J:125719
decreased T cell number J:125719
increased B-1b cell number J:125719
increased pro-B cell number J:125719
Cnn2tm1.1Jin/Cnn2tm1.1Jin
Cnn3tm1.1Hjum/Cnn3tm1.1Hjum
Cd79atm1(cre)Reth/Cd79a+
involves: 129S6/SvEvTac * 129X1/SvJ * BALB/c 		normal immune system phenotype J:237712
Cnn3tm1.1Hjum/Cnn3tm1.1Hjum
Cd79atm1(cre)Reth/Cd79a+
involves: 129S6/SvEvTac * BALB/c 		normal immune system phenotype J:237712
Commd8tm1.1Ksuz/Commd8tm1.1Ksuz
Ightm1Mnz/Igh+
Cd79atm1(cre)Reth/Cd79a+
involves: 129P2/OlaHsd * BALB/c * C57BL/6NSlc * SJL 		abnormal spleen B cell follicle morphology J:278399
Dicer1tm1Mmk/Dicer1tm1.1Mmk
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c 		abnormal immunoglobulin V(D)J recombination J:135783
decreased B cell number J:135783
Dicer1tm1Mmk/Dicer1tm1Mmk
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c 		arrested B cell differentiation J:135783
decreased immature B cell number J:135783
decreased mature B cell number J:135783
decreased pre-B cell number J:135783
increased pro-B cell number J:135783
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(IghelMD4)4Ccg/0
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c 		decreased B cell number J:135783
decreased mature B cell number J:135783
Dnmt1tm2Jae/Dnmt1tm2Jae
Cd79atm1(cre)Reth/Cd79a+
involves: 129S4/SvJae * BALB/c * C57BL/6 		abnormal B cell differentiation J:113645
decreased pro-B cell number J:113645
Ebf1tm1.1Rug/Ebf1tm1.1Rug
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 * SJL 		arrested B cell differentiation J:182210
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm2Sbn/Traf3ip2tm2Sbn
Cd79atm1(cre)Reth/Cd79a+
involves: 129S4/SvJae * BALB/c * C57BL/6 		glomerulonephritis J:191090
increased germinal center B cell number J:191090
increased plasma cell number J:191090
Grb2tm1Lnit/Grb2tm1Lnit
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * BALB/cJ 		abnormal B cell differentiation J:171222
abnormal B cell physiology J:171222
abnormal memory B cell physiology J:171222
decreased B cell number J:171222
decreased follicular B cell number J:171222
decreased IgG3 level J:171222
decreased IgG level J:171222
decreased mature B cell number J:171222
decreased spleen germinal center number J:171222
decreased spleen germinal center size J:171222
decreased transitional stage T1 B cell number J:171222
decreased transitional stage T2 B cell number J:171222
increased B cell apoptosis J:171222
increased B cell proliferation J:171222
increased IgM level J:171222
increased plasma cell number J:171222
Grk2tm1Gwd/Grk2tm1Gwd
Cd79atm1(cre)Reth/Cd79a+
involves: 129 * BALB/c * C57BL/6 		abnormal B cell physiology J:176118
decreased B cell number J:176118
increased B cell number J:176118
increased CD4-positive, alpha-beta T cell number J:176118
increased CD8-positive, alpha-beta T cell number J:176118
increased follicular B cell number J:176118
increased marginal zone B cell number J:176118
Gt(ROSA)26Sortm1(ETV6/SYK)Hjum/Gt(ROSA)26Sor+
Cd79atm3(cre/ERT2)Reth/Cd79a+
involves: 129S6/SvEvTac * BALB/c 		abnormal circulating chemokine level J:208904
abnormal cytokine level J:208904
abnormal plasma cell differentiation J:208904
enlarged lymph nodes J:208904
enlarged spleen J:208904
increased B cell apoptosis J:208904
increased B cell number J:208904
increased B cell proliferation J:208904
increased circulating interferon-gamma level J:208904
increased circulating interleukin-6 level J:208904
increased circulating interleukin-10 level J:208904
increased circulating tumor necrosis factor level J:208904
increased IgM level J:208904
increased interferon-gamma secretion J:208904
increased interleukin-10 secretion J:208904
increased tumor necrosis factor secretion J:208904
Gt(ROSA)26Sortm1(ETV6/SYK)Hjum/Gt(ROSA)26Sor+
Cd79atm3(cre/ERT2)Reth/Cd79a+
Tg(BCL2)22Wehi/0
involves: 129S6/SvEvTac * BALB/c * C57BL/6JWehi * SJL/JWehi 		abnormal B cell physiology J:208904
abnormal plasma cell differentiation J:208904
enlarged lymph nodes J:208904
enlarged spleen J:208904
Gt(ROSA)26Sortm1.1(Ubc-BCL3)Sbn/Gt(ROSA)26Sor+
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		decreased B cell proliferation J:207111
decreased follicular B cell number J:207111
decreased marginal zone B cell number J:207111
increased follicular B cell number J:207111
Gt(ROSA)26Sortm2(CAG-Notch2*)Uzs/Gt(ROSA)26Sor+
Cd79atm1(cre)Reth/Cd79a+
involves: 129S6/SvEvTac * BALB/c * C57BL/6J 		arrested B cell differentiation J:179036
decreased B cell number J:179036
decreased splenocyte number J:179036
increased bone marrow cell number J:179036
increased T cell number J:179036
Hdac1tm1.1Pmt/Hdac1tm1.1Pmt
Hdac2tm1.1Pmt/Hdac2tm1.1Pmt
Cd79atm1(cre)Reth/Cd79a+
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * FVB/N 		abnormal spleen morphology J:157903
arrested B cell differentiation J:157903
decreased B cell number J:157903
decreased bone marrow cell number J:157903
decreased pre-B cell number J:157903
decreased pro-B cell number J:157903
increased B cell apoptosis J:157903
Ikbkgtm1.1Mpa/Ikbkgtm1.1Mpa
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		abnormal B cell differentiation J:113365
decreased B cell number J:113365
decreased mature B cell number J:113365
Ikzf1tm3.1Mbu/Ikzf1tm3.1Mbu
Cd79atm1(cre)Reth/Cd79a+
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL 		decreased pro-B cell number J:209928
Inpp5dtm1Rav/Inpp5dtm1Rav
Cd79atm1(cre)Reth/Cd79a+
Tg(IghAb36-65)1Wys/0
involves: 129 * BALB/c * C57BL/6 * FVB/N 		abnormal B cell anergy J:178833
abnormal B cell negative selection J:178833
decreased B cell number J:178833
increased autoantibody level J:178833
increased plasma cell number J:178833
Nfatc1tm1Rao/Nfatc1tm1Rao
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c 		abnormal B cell calcium ion homeostasis J:177319
abnormal class switch recombination J:177319
abnormal marginal zone B cell physiology J:177319
decreased B cell number J:177319
decreased B cell proliferation J:177319
decreased B-1a cell number J:177319
decreased susceptibility to experimental autoimmune encephalomyelitis J:177319
increased B cell apoptosis J:177319
Nfatc1tm1Rao/Nfatc1tm1Rao
Nfatc2tm1Rao/Nfatc2tm1Rao
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c 		abnormal B cell physiology J:177319
decreased interleukin-2 secretion J:177319
Rnf31tm1.1Kiwa/Rnf31tm1.1Kiwa
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6NCrlj * CBA/JNCrlj 		abnormal B-1 B cell morphology J:201885
abnormal humoral immune response J:201885
decreased B-1a cell number J:201885
decreased B-1b cell number J:201885
decreased IgA level J:201885
decreased IgG1 level J:201885
decreased IgG2a level J:201885
decreased IgG2b level J:201885
decreased IgG3 level J:201885
decreased IgM level J:201885
normal immune system phenotype J:201885
Sh3kbp1tm1Kuro/Sh3kbp1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 * NZB 		abnormal B cell physiology J:176805
abnormal humoral immune response J:176805
abnormal lymphocyte cell number J:176805
decreased B cell number J:176805
decreased B-1a cell number J:176805
decreased follicular B cell number J:176805
decreased immature B cell number J:176805
decreased transitional stage T2 B cell number J:176805
decreased transitional stage T3 B cell number J:176805
normal immune system phenotype J:176805
Sh3kbp1tm1Kuro/Sh3kbp1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+
Gt(ROSA)26Sortm4(Ikbkb)Rsky/?
involves: BALB/c * C57BL/6 * NZB 		decreased B-1a cell number J:176805
normal immune system phenotype J:176805
Srsf3tm1Pjln/Srsf3tm1Pjln
Cd79atm1(cre)Reth/Cd79a+
involves: 129P2/OlaHsd * BALB/c 		decreased B cell number J:113645
decreased pre-B cell number J:113645
decreased pro-B cell number J:113645
Ssbtm1Rjma/Ssbtm2.1Rjma
Cd79atm1(cre)Reth/Cd79a+
involves: 129S/SvEv * BALB/c 		arrested B cell differentiation J:207687
decreased B cell number J:207687
decreased IgG level J:207687
decreased IgM level J:207687
decreased spleen weight J:207687
normal immune system phenotype J:207687
small spleen J:207687
Stim1tm1Kuro/Stim1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		abnormal B cell calcium ion homeostasis J:172608
decreased B cell proliferation J:172608
decreased interleukin-10 secretion J:172608
Stim1tm1Kuro/Stim1tm1Kuro
Stim2tm1.1Kuro/Stim2tm1.1Kuro
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		abnormal B cell calcium ion homeostasis J:172608
abnormal B cell physiology J:172608
decreased B cell proliferation J:172608
decreased interleukin-10 secretion J:172608
demyelination J:172608
normal immune system phenotype J:172608
increased CD4-positive, alpha-beta T cell number J:172608
increased CD8-positive, alpha-beta T cell number J:172608
increased interferon-gamma secretion J:172608
increased interleukin-10 secretion J:172608
increased interleukin-17 secretion J:172608
increased regulatory T cell number J:172608
increased susceptibility to experimental autoimmune encephalomyelitis J:172608
Stim2tm1.1Kuro/Stim2tm1.1Kuro
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		abnormal B cell calcium ion homeostasis J:172608
normal immune system phenotype J:172608
Syktm1Kuro/Syktm1Kuro
Zap70tm1Dlo/Zap70tm1Dlo
Cd79atm1(cre)Reth/?
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		abnormal pro-B cell differentiation J:134528
Tbc1d10ctm1.1Psou/Tbc1d10ctm1.2Psou
Cd79atm1(cre)Reth/Cd79a+
involves: 129S2/SvPas * BALB/c * C57BL/6J 		abnormal B cell physiology J:211913
increased anti-double stranded DNA antibody level J:211913
increased IgG level J:211913
increased IgM level J:211913
increased susceptibility to systemic lupus erythematosus J:211913
Tcf3tm1(PBX1)Mlc/Tcf3+
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		anemia J:226241
arrested B cell differentiation J:226241
decreased B cell number J:226241
decreased immature B cell number J:226241
enlarged liver J:226241
enlarged lymph nodes J:226241
enlarged spleen J:226241
increased B cell acute lymphoblastic leukemia incidence J:226241
increased leukocyte cell number J:226241
thrombocytopenia J:226241
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11/12/2024
MGI 6.24 		The Jackson Laboratory