Cd80 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd80
CD80 antigen
MGI:101775

26 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd80^tm1Lbgn/Cd80^tm1Lbgn C3.Cg-Cd80^tm1Lbgn	abnormal T cell physiology	J:110947
Cd80^tm1Shr/Cd80^tm1Shr involves: 129S4/SvJae	abnormal immunoglobulin level	J:39089
Cd80^tm1Shr/Cd80^tm1Shr involves: 129S4/SvJae	decreased B cell proliferation	J:74662
Tg(Igh-6-Cd80)1Gjf/0 B6.Cg-Tg(Igh-6-Cd80)1Gjf	abnormal T cell number	J:112266
Tg(Igh-6-Cd80)1Gjf/0 B6.Cg-Tg(Igh-6-Cd80)1Gjf	normal hematopoietic system phenotype	J:112266
Tg(Igh-6-Cd80)1Gjf/0 involves: BALB/c * C57BL/6 * CBA	normal hematopoietic system phenotype	J:112266
Tg(Igh-6-Cd80)1Gjf/0 involves: FVB	abnormal CD4-positive, alpha-beta T cell physiology	J:44271
	abnormal humoral immune response	J:112474
	abnormal T cell activation	J:44271
	decreased B cell number	J:44271
	decreased immunoglobulin level	J:112474
Tg(Igh-6-Cd80)1Gjf/0 NOD.FVB-Tg(Igh-6-Cd80)1Gjf/JbsJ	abnormal B cell activation	J:131077
	abnormal bone marrow cell number	J:131077
	abnormal CD8-positive, alpha-beta T cell physiology	J:131077
	abnormal level of surface class II molecules	J:131077
	decreased B cell number	J:131077
	decreased B-2 B cell number	J:131077
	decreased follicular B cell number	J:131077
	decreased IgG1 level	J:131077
	decreased IgG2b level	J:131077
	decreased IgG3 level	J:131077
	decreased IgM level	J:131077
	decreased immature B cell number	J:131077
	decreased immunoglobulin level	J:131077
	decreased mature B cell number	J:131077
	decreased susceptibility to autoimmune diabetes	J:131077
	insulitis	J:131077
Tg(Ins1-Cd80)378Psoh/0 involves: FVB/N	normal endocrine/exocrine gland phenotype	J:209714
Tg(Ins1-Cd80)378Psoh/0 involves: FVB/N	normal homeostasis/metabolism phenotype	J:209714

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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