About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mtf1
metal response element binding transcription factor 1
MGI:101786
25 phenotypes from 6 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mtf1Thyls-BALB/c/Mtf1Thyls-BALB/c
involves: BALB/c * MSM 		increased incidence of tumors by ionizing radiation induction J:71358
increased T cell derived lymphoma incidence J:71358
Mtf1Thyls-BALB/c/Mtf1Thyls-MSM
involves: BALB/c * MSM 		increased incidence of tumors by ionizing radiation induction J:71358, J:85264
increased T cell derived lymphoma incidence J:71358, J:85264
Mtf1tm1b(KOMP)Wtsi/Mtf1+
C57BL/6N-Mtf1tm1b(KOMP)Wtsi/J 		abnormal retina morphology J:211773
decreased circulating glucose level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating potassium level J:211773
Mtf1tm1b(KOMP)Wtsi/Mtf1tm1b(KOMP)Wtsi
C57BL/6N-Mtf1tm1b(KOMP)Wtsi/J 		abnormal craniofacial morphology J:211773
abnormal embryo size J:211773
abnormal forebrain morphology J:211773
anophthalmia J:211773
embryonic growth retardation J:211773
microphthalmia J:211773
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Mtf1tm1Wsc/Mtf1tm1Wsc
involves: 129 * C57BL/6 		hepatic necrosis J:48216
increased cellular sensitivity to alkylating agents J:48216
lethality throughout fetal growth and development, complete penetrance J:48216
Mtf1tm1Wsc/Mtf1tm1Wsc
Not Specified 		dilated liver sinusoidal space J:91119
hepatic necrosis J:91119
lethality throughout fetal growth and development, complete penetrance J:91119
Mtf1tm1Wsc/Mtf1tm1Wsc
Tg(Mx1-cre)1Cgn/0
Tg(UBC-Mtf1)1Wsc/0
involves: 129/Sv * C57BL/6 * CBA 		abnormal xenobiotic pharmacokinetics J:91119
decreased leukocyte cell number J:91119
decreased lymphocyte cell number J:91119
increased physiological sensitivity to xenobiotic J:91119
increased susceptibility to xenobiotic induced morbidity/mortality J:91119
Mtf1tm1Wsc/Mtf1tm1Wsc
Tg(UBC-Mtf1)1Wsc/0
Not Specified 		no abnormal phenotype detected J:91119
Mtf1tm2Wsc/Mtf1tm2Wsc
Tg(Mx1-cre)1Cgn/0
involves: 129 * C57BL/6 * CBA 		abnormal liver physiology J:102512
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory