Fabp5 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fabp5
fatty acid binding protein 5, epidermal
MGI:101790

32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Fabp4^tm1Brsp/Fabp4^tm1Brsp Fabp5^tm1Hota/Fabp5^tm1Hota B6.Cg-Fabp4^tm1Brsp Fabp5^tm1Hota Apoe^tm1Unc	decreased body weight	J:102223
	decreased circulating cholesterol level	J:102223
	decreased circulating glucose level	J:102223
	decreased circulating triglyceride level	J:102223
	decreased susceptibility to atherosclerosis	J:102223
	improved glucose tolerance	J:102223
	increased insulin sensitivity	J:102223
	normal mortality/aging	J:102223
Fabp4^tm1Brsp/Fabp4^tm1Brsp Fabp5^tm1Hota/Fabp5^tm1Hota B6.Cg-Fabp4^tm1Brsp Fabp5^tm1Hota	decreased circulating glucose level	J:111878
	increased insulin sensitivity	J:111878
Fabp4^tm1Brsp/Fabp4^tm1Brsp Fabp5^tm1Hota/Fabp5^tm1Hota involves: 129S7/SvEvBrd * C57BL/6J * SJL	abnormal brown adipose tissue morphology	J:217245
	abnormal brown adipose tissue thermogenesis	J:217245
	decreased body surface temperature	J:217245
	decreased brown adipose tissue mass	J:217245
	decreased circulating glucose level	J:217245
	decreased glycogen level	J:217245
	decreased skeletal muscle glycogen level	J:217245
	decreased triglyceride level	J:217245
	impaired adaptive thermogenesis	J:217245
	increased circulating free fatty acids level	J:217245
	normal muscle phenotype	J:217245
Fabp4^tm1Brsp/Fabp4^tm1Brsp Fabp5^tm1Hota/Fabp5^tm1Hota Lep^ob/Lep^ob B6.Cg-Fabp4^tm1Brsp Fabp5^tm1Hota Lep^ob	abnormal gluconeogenesis	J:111878
	abnormal glucose homeostasis	J:111878
	abnormal glycogen homeostasis	J:111878
	decreased circulating cholesterol level	J:111878
	decreased circulating glucose level	J:111878
	decreased circulating insulin level	J:111878
	decreased circulating triglyceride level	J:111878
	decreased liver triglyceride level	J:111878
	decreased susceptibility to hepatic steatosis	J:111878
	improved glucose tolerance	J:111878
	increased adipocyte glucose uptake	J:111878
	increased body weight	J:111878
	increased fatty acids level	J:111878
	increased insulin sensitivity	J:111878
	increased muscle cell glucose uptake	J:111878
	increased white adipose tissue amount	J:111878
	small liver	J:111878
Fabp5^tm1Hota/Fabp5^tm1Hota Lep^ob/Lep^ob B6.Cg-Fabp5^tm1Hota Lep^ob	improved glucose tolerance	J:111878
	increased insulin sensitivity	J:111878
Fabp5^tm1Hota/Fabp5^tm1Hota Lep^ob/Lep^ob involves: 129 * C57BL/6J * C57BL/10J * SJL	decreased circulating glucose level	J:81609
	improved glucose tolerance	J:81609
	increased circulating insulin level	J:81609
	increased insulin sensitivity	J:81609
	obese	J:81609

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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