F2r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2r
coagulation factor II thrombin receptor
MGI:101802

63 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F2r^tm1Ajc/F2r^tm1Ajc B6.129S4-F2r^tm1Ajc	abnormal bone volume	J:217458
	abnormal cell physiology	J:76348
	abnormal circulating protein level	J:217458
	abnormal neuron apoptosis	J:89774
	abnormal sinus venosus morphology	J:71309
	abnormal urine protein level	J:217458
	abnormal vitelline vasculature morphology	J:71309
	absent vitelline blood vessels	J:71309
	decreased bone trabecular spacing	J:217458
	decreased compact bone thickness	J:217458
	decreased tumor necrosis factor (ligand) superfamily member 11 level	J:217458
	distended pericardium	J:71309
	embryonic growth retardation	J:71309
	embryonic lethality during organogenesis, incomplete penetrance	J:71309
	hemopericardium	J:71309
	hemorrhage	J:71309
	normal homeostasis/metabolism phenotype	J:217458
	increased body weight	J:217458
	increased bone mineral density	J:217458
	increased bone trabecula number	J:217458
	increased compact bone volume	J:217458
	increased trabecular bone volume	J:217458
	increased tumor necrosis factor receptor superfamily member 11b level	J:217458
	increased urine pH	J:217458
	increased urine sodium level	J:217458
	long femur	J:217458
	normal neoplasm	J:92278
	polyuria	J:217458
	normal skeleton phenotype	J:217458
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae	curly tail	J:188121
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae	embryonic lethality during organogenesis, incomplete penetrance	J:33380
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae * C57BL/6	abnormal gallbladder physiology	J:123689
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae * C57BL/6	normal immune system phenotype	J:132733
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae * C57BL/6J	abnormal cell physiology	J:33380
	abnormal placenta development	J:33380
	absent heartbeat	J:33380
	decreased embryo size	J:33380
	embryonic growth retardation	J:33380
	embryonic lethality during organogenesis, incomplete penetrance	J:33380
	normal hematopoietic system phenotype	J:33380
F2r^tm1Pago/F2r^tm1Pago B6.129P2-F2r^tm1Pago	abnormal heart left ventricle morphology	J:142990
	abnormal response to cardiac infarction	J:142990
	normal cardiovascular system phenotype	J:135087
	normal immune system phenotype	J:88245
F2r^tm1Pago/F2r^tm1Pago involves: 129P2/OlaHsd	abnormal cytokine level	J:133917
	abnormal lymph node morphology	J:133917
	decreased susceptibility to endotoxin shock	J:133917
	decreased susceptibility to induced morbidity/mortality	J:133917
	enlarged mesenteric lymph nodes	J:133917
F2r^tm1Pago/F2r^tm1Pago involves: 129P2/OlaHsd * C57BL/6	abnormal blood pressure regulation	J:38032
	abnormal carotid artery morphology	J:103347
	abnormal fertility/fecundity	J:38032
	abnormal intestine physiology	J:96182
	abnormal systemic arterial blood pressure	J:96312
	abnormal systemic arterial blood pressure regulation	J:38032
	abnormal vascular wound healing	J:103347
	normal cardiovascular system phenotype	J:38032, J:124465
	decreased inflammatory response	J:124648
	decreased susceptibility to induced colitis	J:94420
	decreased vascular permeability	J:124465
	embryonic lethality during organogenesis, incomplete penetrance	J:38032
F2r^tm2Cgh/F2r^tm2Cgh involves: 129S4/SvJae * C57BL/6	abnormal cardiovascular system physiology	J:157446
	curly tail	J:157446
	decreased survivor rate	J:157446
	edema	J:157446
	exencephaly	J:157446
	lethality throughout fetal growth and development, incomplete penetrance	J:157446
	spina bifida	J:157446
Tg(Myh6-F2r)18Nmk/0 involves: C57BL/6J	abnormal cardiovascular system physiology	J:142990
	dilated heart left ventricle	J:142990
	enlarged heart	J:142990
	increased heart weight	J:142990

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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