F2r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2r
coagulation factor II thrombin receptor
MGI:101802

63 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F2r^tm1Ajc/F2r^tm1Ajc B6.129S4-F2r^tm1Ajc	abnormal bone volume	J:217458
	abnormal cell physiology	J:76348
	abnormal circulating protein level	J:217458
	abnormal neuron apoptosis	J:89774
	abnormal sinus venosus morphology	J:71309
	abnormal urine protein level	J:217458
	abnormal vitelline vasculature morphology	J:71309
	absent vitelline blood vessels	J:71309
	decreased bone trabecular spacing	J:217458
	decreased compact bone thickness	J:217458
	decreased tumor necrosis factor (ligand) superfamily member 11 level	J:217458
	distended pericardium	J:71309
	embryonic growth retardation	J:71309
	embryonic lethality during organogenesis, incomplete penetrance	J:71309
	hemopericardium	J:71309
	hemorrhage	J:71309
	normal homeostasis/metabolism phenotype	J:217458
	increased body weight	J:217458
	increased bone mineral density	J:217458
	increased bone trabecula number	J:217458
	increased compact bone volume	J:217458
	increased trabecular bone volume	J:217458
	increased tumor necrosis factor receptor superfamily member 11b level	J:217458
	increased urine pH	J:217458
	increased urine sodium level	J:217458
	long femur	J:217458
	normal neoplasm	J:92278
	polyuria	J:217458
	normal skeleton phenotype	J:217458
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae	curly tail	J:188121
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae	embryonic lethality during organogenesis, incomplete penetrance	J:33380
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae * C57BL/6	abnormal gallbladder physiology	J:123689
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae * C57BL/6	normal immune system phenotype	J:132733
F2r^tm1Ajc/F2r^tm1Ajc involves: 129S4/SvJae * C57BL/6J	abnormal cell physiology	J:33380
	abnormal placenta development	J:33380
	absent heartbeat	J:33380
	decreased embryo size	J:33380
	embryonic growth retardation	J:33380
	embryonic lethality during organogenesis, incomplete penetrance	J:33380
	normal hematopoietic system phenotype	J:33380
F2r^tm1Pago/F2r^tm1Pago B6.129P2-F2r^tm1Pago	abnormal heart left ventricle morphology	J:142990
	abnormal response to cardiac infarction	J:142990
	normal cardiovascular system phenotype	J:135087
	normal immune system phenotype	J:88245
F2r^tm1Pago/F2r^tm1Pago involves: 129P2/OlaHsd	abnormal cytokine level	J:133917
	abnormal lymph node morphology	J:133917
	decreased susceptibility to endotoxin shock	J:133917
	decreased susceptibility to induced morbidity/mortality	J:133917
	enlarged mesenteric lymph nodes	J:133917
F2r^tm1Pago/F2r^tm1Pago involves: 129P2/OlaHsd * C57BL/6	abnormal blood pressure regulation	J:38032
	abnormal carotid artery morphology	J:103347
	abnormal fertility/fecundity	J:38032
	abnormal intestine physiology	J:96182
	abnormal systemic arterial blood pressure	J:96312
	abnormal systemic arterial blood pressure regulation	J:38032
	abnormal vascular wound healing	J:103347
	normal cardiovascular system phenotype	J:38032, J:124465
	decreased inflammatory response	J:124648
	decreased susceptibility to induced colitis	J:94420
	decreased vascular permeability	J:124465
	embryonic lethality during organogenesis, incomplete penetrance	J:38032
F2r^tm2Cgh/F2r^tm2Cgh involves: 129S4/SvJae * C57BL/6	abnormal cardiovascular system physiology	J:157446
	curly tail	J:157446
	decreased survivor rate	J:157446
	edema	J:157446
	exencephaly	J:157446
	lethality throughout fetal growth and development, incomplete penetrance	J:157446
	spina bifida	J:157446
Tg(Myh6-F2r)18Nmk/0 involves: C57BL/6J	abnormal cardiovascular system physiology	J:142990
	dilated heart left ventricle	J:142990
	enlarged heart	J:142990
	increased heart weight	J:142990

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24