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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tbp
TATA box binding protein
MGI:101838
24 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tbptm1.1Ees/Tbp+
B6.129X1(Cg)-Tbptm1.1Ees 		embryonic lethality during organogenesis, incomplete penetrance J:77714
fetal growth retardation J:77714
Tbptm1.1Ees/Tbptm1.1Ees
B6.129X1(Cg)-Tbptm1.1Ees 		abnormal blood coagulation J:77714
embryonic lethality during organogenesis, incomplete penetrance J:77714
fetal growth retardation J:77714
hemophagocytosis J:77714
placenta hemorrhage J:77714
postnatal lethality, incomplete penetrance J:77714
Tbptm1Idvd/Tbptm1Idvd
involves: C57BL/6 		embryonic growth arrest J:79959
embryonic lethality at implantation, complete penetrance J:79959
Tbptm1Xjl/Tbp+
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S/SvEv * C57BL/6 * CBA 		abnormal gait J:213011
abnormal Purkinje cell dendrite morphology J:213011
decreased body weight J:213011
impaired balance J:213011
impaired coordination J:213011
kyphosis J:213011
premature death J:213011
Purkinje cell degeneration J:213011
short stride length J:213011
thin cerebellar molecular layer J:213011
Tbptm1Xjl/Tbptm1Xjl
Tg(Nes-cre)1Kln/?
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal nest building behavior J:221703
cerebellum hypoplasia J:221703
decreased body size J:221703
decreased locomotor activity J:221703
hunched posture J:221703
impaired coordination J:221703
slow postnatal weight gain J:221703
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory