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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tcf12
transcription factor 12
MGI:101877
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tcf12tm1Zhu/Tcf12+
Tcf3tm1Wein/Tcf3+
involves: 129S4/SvJaeSor 		decreased pro-B cell number J:43324
postnatal growth retardation J:43324
postnatal lethality, incomplete penetrance J:43324
Tcf12tm1Zhu/Tcf12+
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Lck-cre)#Zhu/0
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * SJL 		abnormal T cell differentiation J:75746
increased double-negative T cell number J:75746
increased single-positive T cell number J:75746
Tcf12tm1Zhu/Tcf12+
Tcf4tm1Zhu/Tcf4+
involves: 129P2/OlaHsd * 129S7/SvEvBrd 		decreased pro-B cell number J:43324
normal nervous system phenotype J:125313
postnatal growth retardation J:43324
postnatal lethality, complete penetrance J:43324
Tcf12tm1Zhu/Tcf12tm2Zhu
involves: 129S7/SvEvBrd 		arrested T cell differentiation J:120411
Tcf12tm2Zhu/Tcf12+
Not Specified 		normal hematopoietic system phenotype J:120411
seizures J:120411
Tcf12tm2Zhu/Tcf12tm2Zhu
Not Specified 		abnormal B cell differentiation J:120411
abnormal response to transplant J:120411
abnormal T cell differentiation J:120411
absent T cells J:120411
arrested T cell differentiation J:120411
decreased double-positive T cell number J:120411
decreased immature B cell number J:120411
decreased pre-B cell number J:120411
decreased pro-B cell number J:120411
decreased thymocyte number J:120411
exencephaly J:120411
increased double-negative T cell number J:120411
postnatal growth retardation J:120411
postnatal lethality, incomplete penetrance J:120411
thymus hypoplasia J:120411
Tcf12tm2Zhu/Tcf12tm2Zhu
Tg(TcrAND)53Hed/0
involves: C57BL/6 * SJL 		abnormal CD4-positive, alpha beta T cell morphology J:120411
abnormal T cell subpopulation ratio J:120411
arrested T cell differentiation J:120411
increased T cell number J:120411
Tcf12tm3Zhu/Tcf12tm3Zhu
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Cd4-cre)1Cwi/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 		abnormal CD8-positive, alpha beta T cell morphology J:129171
abnormal T cell differentiation J:129171
decreased CD4-positive, alpha-beta T cell number J:129171
increased CD8-positive, alpha-beta T cell number J:129171
Tcf12tm3Zhu/Tcf12tm3Zhu
Tcf3tm4Zhu/Tcf3tm4Zhu
Tg(Lck-cre)#Zhu/0
involves: 129S4/SvJae * C57BL/6 * SJL/J 		decreased double-positive T cell number J:129570
decreased T cell number J:129570
increased double-negative T cell number J:129570
increased T cell proliferation J:129570
thymus hypoplasia J:129570
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory