Pou5f1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pou5f1
POU domain, class 5, transcription factor 1
MGI:101893

21 phenotypes from 8 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Alpl^tm1(cre)Nagy/Alpl⁺ Pou5f1^tm1Scho/Pou5f1^tm1.1Scho involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal gonadal ridge morphology	J:95317
	absent ovarian follicles	J:95317
	decreased primordial germ cell number	J:95317
	decreased primordial ovarian follicle number	J:95317
	female infertility	J:95317
	increased Leydig cell number	J:95317
	oligozoospermia	J:95317
	reduced male fertility	J:95317
	small seminiferous tubules	J:95317
Gt(ROSA)26Sor^{tm1(cre/ERT)Brn}/Gt(ROSA)26Sor^{tm1(cre/ERT)Brn} Pou5f1^tm1Jnic/Pou5f1^tm1Jnic involves: 129P2/OlaHsd	abnormal inner cell mass morphology	J:208425
	abnormal primitive endoderm morphology	J:208425
Pou5f1^{tm1.1(cre/Esr1)Yseg}/Pou5f1⁺ C57BL/6-Pou5f1^{tm1.1(cre/Esr1)Yseg}	no abnormal phenotype detected	J:194647
Pou5f1^tm1Cgre/Pou5f1^tm1Cgre either: 129P2/OlaHsd or (involves: 129P2/OlaHsd * CBA) or (involves: 129P2/OlaHsd * MF1)	absent inner cell mass	J:51139
	embryonic lethality between implantation and somite formation, complete penetrance	J:51139
Pou5f1^tm1Grc/Pou5f1^tm1Grc involves: 129S6/SvEvTac * C57BL/6	prenatal lethality, complete penetrance	J:199710
Pou5f1^tm1Jae/Pou5f1^tm1Jae involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:130250
Pou5f1^tm1Scho/Pou5f1^tm1Scho Tg(Krt1-15-cre/PGR)22Cot/0 involves: 129P2/OlaHsd C57BL/6J * SJL/J	normal integument phenotype	J:130248
Pou5f1^tm1Scho/Pou5f1^tm1Scho Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	normal hematopoietic system phenotype	J:130248
	normal liver/biliary system phenotype	J:130248
Pou5f1^tm1Scho/Pou5f1^tm1Scho Tg(Nes-cre)1Atp/0 involves: 129P2/OlaHsd * FVB/N	normal behavior/neurological phenotype	J:130248
	normal nervous system phenotype	J:130248
Pou5f1^tm1Scho/Pou5f1^tm1Scho Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	normal digestive/alimentary phenotype	J:130248
Pou5f1^tm2Jae/Pou5f1^tm2Jae involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:130248

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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