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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pou3f4
POU domain, class 3, transcription factor 4
MGI:101894
43 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pou3f4sdl/Y
C3HeB/FeJ-Pou3f4sdl 		circling J:220419
head tossing J:220419
impaired hearing J:220419
increased circulating potassium level J:220419
Pou3f4sdl/Pou3f4sdl
C3HeB/FeJ-Pou3f4sdl 		abnormal stria vascularis morphology J:220419
abnormal vestibular system physiology J:220419
absent startle reflex J:220419
circling J:220419
cochlear outer hair cell degeneration J:220419
deafness J:220419
decreased cochlea coiling J:220419
head tossing J:220419
normal hearing/vestibular/ear phenotype J:220419
impaired swimming J:220419
increased circulating potassium level J:220419
increased or absent threshold for auditory brainstem response J:220419
Pou3f4Slf/Y
C3H101H-Pou3f4Slf 		abnormal spiral ligament fibrocyte morphology J:59387
abnormal superior semicircular canal morphology J:59387
head shaking J:13743
Pou3f4Slf/Pou3f4Slf
C3H101H-Pou3f4Slf 		abnormal pinna reflex J:59387
abnormal spiral ligament fibrocyte morphology J:59387
abnormal superior semicircular canal morphology J:59387
head shaking J:13743
Pou3f4tm1Cren/Y
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal bony labyrinth J:56294
abnormal cochlea morphology J:56294
abnormal gait J:56294
abnormal internal auditory canal morphology J:56294
abnormal lateral semicircular canal morphology J:56294
abnormal oval window morphology J:94058
abnormal pinna reflex J:56294
abnormal Reissner membrane morphology J:56294
abnormal scala tympani morphology J:56294
abnormal spiral ligament fibrocyte morphology J:56294
abnormal spiral limbus morphology J:56294
abnormal stapes crus morpholgy J:94058
abnormal stapes footplate morphology J:56294, J:94058
abnormal stapes morphology J:56294, J:94058
abnormal subarcuate fossa morphology J:56294
abnormal superior semicircular canal morphology J:56294, J:112541
abnormal temporal bone morphology J:56294
conductive hearing loss J:94058
deafness J:56294
decreased cochlea coiling J:56294
decreased endocochlear potential J:94058
dilated endolymphatic duct J:56294
distended Reissner membrane J:56294
head bobbing J:56294
increased or absent threshold for auditory brainstem response J:94058
sensorineural hearing loss J:94058
short vibrissae J:56294
small scala tympani J:56294
Pou3f4tm1Tno/Y
involves: 129S4/SvJae * C57BL/6 		abnormal cochlea morphology J:57298
abnormal type I spiral ligament fibrocytes J:57298
abnormal type II spiral ligament fibrocytes J:57298
normal behavior/neurological phenotype J:57298
deafness J:57298
decreased endocochlear potential J:57298
increased or absent threshold for auditory brainstem response J:57298
Pou3f4tm1Tno/Pou3f4+
involves: 129S4/SvJae * C57BL/6 		abnormal cochlea morphology J:108889
abnormal type II spiral ligament fibrocytes J:108889
deafness J:108889
detached Reissner membrane J:108889
increased or absent threshold for auditory brainstem response J:108889
Pou3f4tm1Tno/Pou3f4tm1Tno
involves: 129S4/SvJae * C57BL/6 		abnormal cochlea morphology J:57298
abnormal spiral ligament fibrocyte morphology J:57298
abnormal type I spiral ligament fibrocytes J:57298
abnormal type II spiral ligament fibrocytes J:57298, J:108889
normal behavior/neurological phenotype J:57298
deafness J:57298, J:108889
decreased endocochlear potential J:57298
detached Reissner membrane J:108889
increased or absent threshold for auditory brainstem response J:57298, J:108889
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory