Pou2f2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pou2f2
POU domain, class 2, transcription factor 2
MGI:101897

13 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pou2f2^tm1Bal/Pou2f2⁺ involves: 129S2/SvPas	decreased IgG1 level	J:4555
	decreased IgM level	J:4555
	decreased mature B cell number	J:4555
Pou2f2^tm1Bal/Pou2f2^tm1Bal involves: 129S2/SvPas	abnormal suckling behavior	J:4555
	cyanosis	J:4555
	decreased IgG1 level	J:4555
	decreased IgM level	J:4555
	decreased mature B cell number	J:4555
	dehydration	J:4555
	lethargy	J:4555
	neonatal lethality, complete penetrance	J:4555
	normal respiratory system phenotype	J:4555
Pou2f2^tm1Bal/Pou2f2^tm1Bal involves: 129S2/SvPas * C57BL/6	arrested B cell differentiation	J:88240
	decreased B cell number	J:88240
	decreased immunoglobulin level	J:88240
	neonatal lethality, complete penetrance	J:88240
Pou2f2^tm1Lmc/Pou2f2^tm1Lmc involves: C57BL/6	arrested B cell differentiation	J:88240
	decreased B cell number	J:88240
	decreased B-1 B cell number	J:88240
	decreased immunoglobulin level	J:88240
	neonatal lethality, complete penetrance	J:88240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24