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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pla2g5
phospholipase A2, group V
MGI:101899
24 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pla2g5em1(IMPC)Ccpcz/Pla2g5em1(IMPC)Ccpcz
C57BL/6NCrl-Pla2g5em1(IMPC)Ccpcz/Ccpcz 		abnormal lymph node morphology J:211773
abnormal sinus arrhythmia J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
abnormal thymus morphology J:211773
cardiovascular system phenotype J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
enlarged thymus J:211773
increased circulating alkaline phosphatase level J:211773
increased eosinophil cell number J:211773
increased startle reflex J:211773
prolonged RR interval J:211773
small testis J:211773
Pla2g5tm1.1Kiku/Pla2g5tm1.1Kiku
involves: 129 * C57BL/6 		abnormal cardiac muscle contractility J:186024
abnormal cardiomyocyte apoptosis J:186024
abnormal myocardial fiber physiology J:186024
abnormal response to cardiac infarction J:186024
decreased myocardial infarct size J:186024
decreased physiological sensitivity to xenobiotic J:186024
Pla2g5tm1Jarm/Pla2g5tm1Jarm
B6.129-Pla2g5tm1Jarm 		normal immune system phenotype J:197334
impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
C.129-Pla2g5tm1Jarm 		impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
involves: 129 * BALB/c 		impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
involves: 129 * C57BL/6 		impaired macrophage phagocytosis J:110309
Pla2g5tm1Jarm/Pla2g5tm1Jarm
involves: 129 * C57BL/6J 		abnormal macrophage physiology J:89490
decreased acute inflammation J:89490
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory