Pla2g5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pla2g5
phospholipase A2, group V
MGI:101899

24 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pla2g5^{em1(IMPC)Ccpcz}/Pla2g5^{em1(IMPC)Ccpcz} C57BL/6NCrl-Pla2g5^{em1(IMPC)Ccpcz}/Ccpcz	abnormal lymph node morphology	J:211773
	abnormal sinus arrhythmia	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal thymus morphology	J:211773
	cardiovascular system phenotype	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased eosinophil cell number	J:211773
	increased startle reflex	J:211773
	small testis	J:211773
Pla2g5^tm1.1Kiku/Pla2g5^tm1.1Kiku involves: 129 * C57BL/6	abnormal cardiac muscle contractility	J:186024
	abnormal cardiomyocyte apoptosis	J:186024
	abnormal myocardial fiber physiology	J:186024
	abnormal response to cardiac infarction	J:186024
	decreased myocardial infarct size	J:186024
	decreased physiological sensitivity to xenobiotic	J:186024
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm B6.129-Pla2g5^tm1Jarm	normal immune system phenotype	J:197334
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm B6.129-Pla2g5^tm1Jarm	impaired macrophage phagocytosis	J:110309
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm C.129-Pla2g5^tm1Jarm	impaired macrophage phagocytosis	J:110309
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm involves: 129 * BALB/c	impaired macrophage phagocytosis	J:110309
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm involves: 129 * C57BL/6	impaired macrophage phagocytosis	J:110309
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm involves: 129 * C57BL/6J	abnormal macrophage physiology	J:89490
Pla2g5^tm1Jarm/Pla2g5^tm1Jarm involves: 129 * C57BL/6J	decreased acute inflammation	J:89490

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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