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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
MGI:101900
53 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Mmp14tm1Hbh/Mmp14+
Mmp16tm1Khol/Mmp16+
involves: 129P2/OlaHsd * 129S6/SvEvTac
abnormal chondrocyte morphology J:130212
decreased cranium length J:130212
short humerus J:130212
Mmp14tm1Hbh/Mmp14+
Mmp16tm1Khol/Mmp16tm1Khol
involves: 129P2/OlaHsd * 129S6/SvEvTac
abnormal chondrocyte morphology J:130212
abnormal compact bone morphology J:130212
decreased bone ossification J:130212
decreased cranium length J:130212
frontal bone hypoplasia J:130212
nasal bone hypoplasia J:130212
parietal bone hypoplasia J:130212
postnatal lethality, incomplete penetrance J:130212
short femur J:130212
short humerus J:130212
short snout J:130212
thin neurocranium J:130212
Mmp14tm1Hbh/Mmp14tm1.1Khol
Mmp15tm1Kohl/Mmp15tm1Kohl
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * CBA
abnormal placental labyrinth vasculature morphology J:167396
absent placental labyrinth J:167396
normal endocrine/exocrine gland phenotype J:167396
Mmp14tm1Hbh/Mmp14tm1Hbh
Mmp15tm1Kohl/Mmp15tm1Kohl
involves: 129P2/OlaHsd * 129S6/SvEvTac
abnormal placenta labyrinth morphology J:167396
abnormal placental labyrinth vasculature morphology J:167396
decreased embryo size J:167396
dilated vasculature J:167396
embryonic growth retardation J:167396
embryonic lethality during organogenesis, complete penetrance J:167396
enlarged pericardium J:167396
Mmp14tm1Hbh/Mmp14tm1Hbh
Mmp16tm1Khol/Mmp16+
involves: 129P2/OlaHsd * 129S6/SvEvTac
abnormal cartilage morphology J:130212
abnormal chondrocyte morphology J:130212
abnormal compact bone morphology J:130212
abnormal long bone epiphyseal plate proliferative zone J:130212
abnormal long bone hypertrophic chondrocyte zone J:130212
abnormal long bone morphology J:130212
decreased bone ossification J:130212
frontal bone hypoplasia J:130212
nasal bone hypoplasia J:130212
parietal bone hypoplasia J:130212
postnatal lethality, complete penetrance J:130212
short femur J:130212
short humerus J:130212
thin neurocranium J:130212
Mmp14tm1Hbh/Mmp14tm1Hbh
Mmp16tm1Khol/Mmp16tm1Khol
involves: 129P2/OlaHsd * 129S6/SvEvTac
abnormal cartilage morphology J:130212
abnormal chondrocyte morphology J:130212
abnormal compact bone morphology J:130212
abnormal cranium morphology J:130212
abnormal long bone epiphyseal plate proliferative zone J:130212
abnormal long bone hypertrophic chondrocyte zone J:130212
abnormal long bone morphology J:130212
abnormal mandible morphology J:130212
abnormal Meckel's cartilage morphology J:130212
abnormal midface morphology J:130212
abnormal parietal bone morphology J:130212
abnormal skeleton morphology J:130212
abnormal vomer bone morphology J:130212
absent bone trabeculae J:130212
absent palatine bone J:130212
cleft secondary palate J:130212
decreased body size J:130212
decreased bone ossification J:130212
domed cranium J:130212
frontal bone hypoplasia J:130212
maxilla hypoplasia J:130212
nasal bone hypoplasia J:130212
neonatal lethality, complete penetrance J:130212
palatal shelf hypoplasia J:130212
palatal shelves fail to meet at midline J:130212
parietal bone hypoplasia J:130212
pterygoid bone hypoplasia J:130212
short femur J:130212
short humerus J:130212
short limbs J:130212
short snout J:130212
thin neurocranium J:130212
vomer bone hypoplasia J:130212
Mmp14tm1Noda/Mmp14+
Mmp2tm1Ito/Mmp2tm1Ito
Not Specified
decreased body weight J:91198
Mmp14tm1Noda/Mmp14tm1Noda
Mmp2tm1Ito/Mmp2tm1Ito
Not Specified
abnormal blood vessel morphology J:91198
abnormal bone ossification J:91198
abnormal skeletal muscle morphology J:91198
abnormal skeleton morphology J:91198
cyanosis J:91198
decreased birth weight J:91198
delayed muscle development J:91198
neonatal lethality, complete penetrance J:91198
thin diaphragm muscle J:91198

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory