F2rl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2rl1
F2R like trypsin receptor 1
MGI:101910

28 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F2rl1^{tm1b(EUCOMM)Wtsi}/F2rl1^{tm1b(EUCOMM)Wtsi} C57BL/6N-F2rl1^{tm1b(EUCOMM)Wtsi}/J	increased startle reflex	J:211773
F2rl1^tm1Bpd/F2rl1^tm1Bpd B6.129P2-F2rl1^tm1Bpd	normal cardiovascular system phenotype	J:135087
	decreased susceptibility to endotoxin shock	J:88245
	normal immune system phenotype	J:88245
F2rl1^tm1Bpd/F2rl1^tm1Bpd involves: 129P2/OlaHsd	abnormal thermal nociception	J:127006
F2rl1^tm1Bpd/F2rl1^tm1Bpd involves: 129P2/OlaHsd * C57BL/6	abnormal pain threshold	J:124648
	decreased inflammatory response	J:124648
	increased inflammatory response	J:96196
	increased susceptibility to induced pancreatitis	J:96196
F2rl1^tm1Bpd/F2rl1^tm1Bpd involves: 129P2/OlaHsd * C57BL/6J	abnormal systemic arterial blood pressure	J:96312
	perinatal lethality, incomplete penetrance	J:96312
	postnatal lethality, incomplete penetrance	J:96312
F2rl1^tm1Cgh/F2rl1^tm1Cgh B6.129S4-F2rl1^tm1Cgh	decreased dendritic cell number	J:113591
F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae	abnormal skin physiology	J:111734, J:130935
F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae * C57BL/6	abnormal gallbladder physiology	J:123689
	abnormal glucose homeostasis	J:130781
	decreased susceptibility to injury	J:124303
	glomerulonephritis	J:124303
	normal immune system phenotype	J:132733
	impaired leukocyte tethering or rolling	J:76626
	improved glucose tolerance	J:130781
F2rl1^tm1Jkaw/F2rl1^tm1Jkaw involves: 129P2/OlaHsd * C57BL/6	decreased susceptibility to type IV hypersensitivity reaction	J:106127
F2rl1^tm1Mslb/F2rl1^tm1Mslb involves: 129X1/SvJ * C57BL/6	decreased IgE level	J:79757
F2rl1^tm1Mslb/F2rl1^tm1Mslb involves: 129X1/SvJ * C57BL/6	decreased inflammatory response	J:79757
F2rl1^tm1Wrf/F2rl1^tm1Wrf involves: 129P2/OlaHsd	abnormal physiological response to xenobiotic	J:81119, J:120751
	decreased circulating interleukin-18 level	J:102762
	liver inflammation	J:102762
F2rl1^tm1Wrf/F2rl1^tm1Wrf involves: 129P2/OlaHsd * C57BL/6	decreased physiological sensitivity to xenobiotic	J:81119
	decreased susceptibility to induced arthritis	J:81119
	increased cerebral infarct size	J:112482

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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