Akr1b7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akr1b7
aldo-keto reductase family 1, member B7
MGI:101918

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akr1b7^tm1.1Anm/Akr1b7^tm1.1Anm involves: 129	abnormal white adipose tissue physiology	J:208505
	normal behavior/neurological phenotype	J:208505
	decreased energy expenditure	J:208505
	decreased food intake	J:208505
	decreased respiratory quotient	J:208505
	hepatic steatosis	J:208505
	normal homeostasis/metabolism phenotype	J:208505
	increased body weight	J:208505
	increased circulating adiponectin level	J:208505
	increased circulating glycerol level	J:208505
	increased circulating insulin level	J:208505
	increased circulating leptin level	J:208505
	increased circulating triglyceride level	J:208505
	increased gonadal fat pad weight	J:208505
	increased inguinal fat pad weight	J:208505
	increased liver triglyceride level	J:208505
	increased liver weight	J:208505
	increased susceptibility to diet-induced obesity	J:208505
	increased white adipose tissue amount	J:208505
	increased white fat cell size	J:208505
	insulin resistance	J:208505
Akr1b7^tm1.1Fth/Akr1b7^tm1.1Fth involves: 129P2/OlaHsd * C57BL/6	decreased circulating progesterone level	J:123295
	increased circulating progesterone level	J:123295
	normal reproductive system phenotype	J:123295

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24