Ap1g1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
MGI:101919

38 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ap1g1^fgt/Ap1g1^fgt C57BL/6-Ap1g1^fgt/KjnBoc	abnormal thyroid follicle morphology	J:230572
	abnormal thyroid follicular cell morphology	J:230572
	abnormal thyroid gland morphology	J:230572
	asthenozoospermia	J:230572
	choroidal neovascularization	J:230572
	circling	J:230572
	cochlear outer hair cell degeneration	J:230572
	decreased body weight	J:230572
	decreased circulating thyroxine level	J:230572
	decreased cochlear outer hair cell number	J:230572
	decreased male germ cell number	J:230572
	decreased vestibular hair cell number	J:230572
	head tilt	J:230572
	head tossing	J:230572
	impaired swimming	J:230572
	increased or absent threshold for auditory brainstem response	J:230572
	increased susceptibility to age-related retinal degeneration	J:230572
	kinked sperm flagellum	J:230572
	oligozoospermia	J:230572
	organ of Corti degeneration	J:230572
	reduced male fertility	J:230572
	retina spots	J:230572
	vestibular hair cell degeneration	J:230572
Ap1g1^fgt/Ap1g1^fgt involves: C3HeB/FeJ * C57BL/6J	circling	J:230572
Ap1g1^fgt/Ap1g1^fgt involves: C3HeB/FeJ * C57BL/6J	head tossing	J:230572
Ap1g1^{tm1b(EUCOMM)Hmgu}/Ap1g1⁺ B6N(Cg)-Ap1g1^{tm1b(EUCOMM)Hmgu}/J	abnormal optic disk morphology	J:211773
	abnormal retina morphology	J:211773
	cataract	J:211773
	decreased bone mineral content	J:211773
	decreased lean body mass	J:211773
	hyperactivity	J:211773
	increased total body fat amount	J:211773
	increased vertical activity	J:211773
Ap1g1^{tm1b(EUCOMM)Hmgu}/Ap1g1^{tm1b(EUCOMM)Hmgu} B6N(Cg)-Ap1g1^{tm1b(EUCOMM)Hmgu}/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Ap1g1^tm1Schu/Ap1g1⁺ either: (involves: 129P2/OlaHsd * 129X1/SvJ) or (involves: 129P2/OlaHsd * C57BL/6J)	decreased body size	J:53252
	decreased CD4-positive, alpha-beta T cell number	J:53252
	postnatal growth retardation	J:53252
	slow postnatal weight gain	J:53252
Ap1g1^tm1Schu/Ap1g1^tm1Schu either: (involves: 129P2/OlaHsd * 129X1/SvJ) or (involves: 129P2/OlaHsd * C57BL/6J)	embryonic lethality before implantation, complete penetrance	J:53252

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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