Tnc Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnc
tenascin C
MGI:101922

16 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnc^tm1Msch/Tnc^tm1Msch either: B6.129-Tnc^tm1Msch or (involves: 129S1/Sv * 129X1/SvJ * C57Bl/6J)	abnormal circardian behavior entrainment	J:107157
	abnormal response to novel object	J:107157
	decreased anxiety-related response	J:107157
	decreased grip strength	J:107157
	impaired passive avoidance behavior	J:107157
Tnc^tm1Msch/Tnc^tm1Msch involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	impaired synaptic plasticity	J:78340
	reduced long-term potentiation	J:78340
Tnc^tm1Ref/Tnc^tm1Ref involves: 129/Sv * 129S2/SvPas	no abnormal phenotype detected	J:33828
Tnc^tm1Sia/Tnc^tm1Sia involves: BALB/c * C57BL/6 * CBA	no abnormal phenotype detected	J:36890
Tnc^tm1Sia/Tnc^tm1Sia involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	normal hearing/vestibular/ear phenotype	J:53565
Tnc^tm1Sia/Tnc^tm1Sia involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj	abnormal circadian behavior	J:32517
	abnormal CNS synaptic transmission	J:32517
	abnormal serotonin level	J:32517
	decreased dopamine level	J:32517
	impaired swimming	J:32517
	increased locomotor activity	J:32517
	increased stereotypic behavior	J:32517

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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