Slc1a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
MGI:101931

21 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc1a2^tm1.1Ncd/Slc1a2^tm1.1Ncd Tg(Ins2-cre)25Mgn/0 B6.Cg-Slc1a2^tm1.1Ncd Tg(Ins2-cre)25Mgn	no abnormal phenotype detected	J:207177
Slc1a2^tm1.1Ncd/Slc1a2^tm1.1Ncd Tg(Nes-cre)1Kln/0 B6.Cg-Slc1a2^tm1.1Ncd Tg(Nes-cre)1Kln	decreased survivor rate	J:207177
	hyperactivity	J:207177
	premature death	J:207177
	seizures	J:207177
	slow postnatal weight gain	J:207177
Slc1a2^tm1.1Ncd/Slc1a2^tm1.1Ncd Tg(Pdx1-cre)1Heed/0 involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:207177
Slc1a2^tm1.1Pros/Slc1a2^tm1.1Pros Tg(GFAP-cre/ERT2)13Kdmc/0 involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6	abnormal brain wave pattern	J:221590
	normal behavior/neurological phenotype	J:221590
	normal nervous system phenotype	J:221590
	premature death	J:221590
	seizures	J:221590
	slow postnatal weight gain	J:221590
Slc1a2^tm1.1Pros/Slc1a2^tm1.1Pros Tg(Syn1-cre)671Jxm/0 involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6	abnormal synaptic physiology	J:221590
	normal behavior/neurological phenotype	J:221590
	normal growth/size/body region phenotype	J:221590
	normal mortality/aging	J:221590
Slc1a2^tm1Kta/Slc1a2⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal cell physiology	J:144898
Slc1a2^tm1Kta/Slc1a2^tm1Kta B6.129P2-Slc1a2^tm1Kta	postnatal lethality, complete penetrance	J:124191
Slc1a2^tm1Kta/Slc1a2^tm1Kta involves: 129P2/OlaHsd * C57BL/6	abnormal hippocampus CA1 region morphology	J:40984
	abnormal telencephalon morphology	J:40984
	cerebral edema	J:40984
	convulsive seizures	J:40984
	hippocampus pyramidal cell degeneration	J:84859
	increased susceptibility to pharmacologically induced seizures	J:40984
	postnatal growth retardation	J:40984
	premature death	J:40984

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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