Hmgcs2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hmgcs2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
MGI:101939

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fgfr2^tm3.1Lni/Fgfr2⁺ Hmgcs2^em1Wilh/Hmgcs2^em1Wilh involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal reproductive system phenotype	J:285178
Hmgcs2^tm1.1Yil/Hmgcs2^tm1.1Yil Lgr5^{tm3(cre/ERT2)Cle}/Lgr5⁺ Gt(ROSA)26Sor^{tm9(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ involves: 129S6/SvEvTac * C3H * C57BL/6J * C57BL/6NCrl	abnormal intestinal crypt stem cell physiology	J:280699
	abnormal jejunal goblet cell morphology	J:280699
	abnormal jejunum crypts of Lieberkuhn morphology	J:280699
	abnormal response to radiation	J:280699
	enhanced intestine regeneration	J:280699
	impaired intestine regeneration	J:280699
	increased Paneth cell number	J:280699

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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