Nfatc2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
MGI:102463

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nfatc1^tm1Rao/Nfatc1^tm1Rao Nfatc2^tm1Rao/Nfatc2^tm1Rao Cd79a^tm1(cre)Reth/Cd79a⁺ involves: BALB/c	abnormal B cell physiology	J:177319
	decreased interleukin-2 secretion	J:177319
Nfatc2^tm1Glm/Nfatc2^tm1Glm Nfatc3^{tm1c(EUCOMM)Hmgu}/Nfatc3^{tm1c(EUCOMM)Hmgu} Tg(Itgax-cre)1-1Reiz/0 involves: C57BL/6 * C57BL/6N * CBA	decreased interleukin-2 secretion	J:346703
Nfatc2^tm1Glm/Nfatc2^tm1Glm Nfatc3^tm1Glm/Nfatc3^tm1Glm involves: 129S2/SvPas	abnormal lymph node morphology	J:51339
	abnormal lymphocyte cell number	J:51339
	blepharitis	J:51339
	decreased T cell number	J:51339
	enlarged spleen	J:51339
	increased B cell number	J:51339
	increased inflammatory response	J:51339
	increased T cell number	J:51339
	interstitial pneumonia	J:51339
	postnatal growth retardation	J:51339
Nfatc2^tm1Glm/Nfatc2^tm1Glm Nfatc3^tm1Glm/Nfatc3^tm1Glm Nfatc4^tm1Grc/Nfatc4^tm1Grc involves: 129S2/SvPas	abnormal locomotor activation	J:109139
	abnormal sensory neuron innervation pattern	J:83744
	abnormal social/conspecific interaction behavior	J:109139
	abnormal spinal cord dorsal column morphology	J:83744
	abnormal trigeminal nerve morphology	J:83744
	decreased anxiety-related response	J:109139
	decreased embryo size	J:83744
	decreased grip strength	J:109139
	hypotonia	J:109139
Nfatc2^tm1Glm/Nfatc2^tm1Glm Nfatc4^tm1Grc/Nfatc4^tm1Grc involves: 129S2/SvPas	abnormal cranium morphology	J:109139
	abnormal locomotor activation	J:109139
	abnormal mandible morphology	J:109139
	abnormal neurocranium morphology	J:109139
	abnormal social/conspecific interaction behavior	J:109139
	abnormal zygomatic arch morphology	J:109139
	decreased anxiety-related response	J:109139
	decreased grip strength	J:109139
	hypotonia	J:109139
Nfatc2^tm1Rao/Nfatc2^tm1Rao Nfatc3^tm1Grc/Nfatc3^tm1Grc Tg(Lck-cre)I57Jxm/0 involves: ICR	abnormal double-negative T cell morphology	J:141917
	abnormal T cell differentiation	J:141917
	increased T cell apoptosis	J:141917

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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