Pou4f1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pou4f1
POU domain, class 4, transcription factor 1
MGI:102525

26 phenotypes from 8 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pou4f1^{tm1.1(cre)Tcba}/Pou4f1^{tm1.1(cre)Tcba} involves: 129 * C57BL/6	no abnormal phenotype detected	J:215125
Pou4f1^tm1.1Gan/Pou4f1^tm1.1Gan Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 C57BL/6J * CBA	normal vision/eye phenotype	J:215207
Pou4f1^tm1Dsl/Pou4f1^tm1Dsl either: 129X1/SvJ-Pou4f1^tm1Dsl or (involves: 129X1/SvJ * C57BL/6J)	abnormal trigeminal ganglion morphology	J:103665
	perinatal lethality, complete penetrance	J:103665
Pou4f1^tm1Et/Pou4f1^tm1Nat involves: 129/Sv * 129S4/SvJae * 129S7/SvEvBrd	neonatal lethality	J:123264
	normal vision/eye phenotype	J:123264
Pou4f1^tm1Nat/Pou4f1^tm1Nat involves: 129S7/SvEvBrd	abnormal trigeminal nerve morphology	J:67059
Pou4f1^tm1Nat/Pou4f1^tm1Nat involves: 129S7/SvEvBrd * C57BL/6J	abnormal cranial ganglia morphology	J:35877
	abnormal epithalamus morphology	J:35877
	abnormal medulla oblongata morphology	J:35877
	abnormal red nucleus morphology	J:35877
	abnormal vestibular ganglion morphology	J:70744
	absent gastric milk in neonates	J:35877
	absent suckling reflex	J:35877
	cochlear ganglion hypoplasia	J:70744
	impaired righting response	J:35877
	neonatal lethality, complete penetrance	J:35877
	small geniculate ganglion	J:70744
	small trigeminal ganglion	J:35877, J:54859
Pou4f1^tm1Nat/Pou4f1^tm2.1Nat Tg(Pax6-cre,GFP)2Pgr/0 involves: 129 * 129S7/SvEvBrd	abnormal retina ganglion cell morphology	J:147350
Pou4f1^tm1Rsd/Pou4f1^tm1Rsd involves: 129S4/SvJae	abnormal hindbrain morphology	J:37118
	abnormal inferior olivary complex morphology	J:37118
	abnormal stationary movement	J:37118
	absent red nucleus	J:37118
	aphagia	J:37118
	cochlear ganglion hypoplasia	J:37118
	impaired righting response	J:37118
	neonatal lethality, complete penetrance	J:37118
	small dorsal root ganglion	J:37118
	small trigeminal ganglion	J:37118
Pou4f1^tm2Dsl/Pou4f1^tm2Dsl either: 129X1/SvJ-Pou4f1^tm2Dsl or (involves: 129X1/SvJ * C57BL/6J)	abnormal dorsal root ganglion morphology	J:103665

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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