Tbx6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbx6
T-box 6
MGI:102539

19 phenotypes from 6 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbx6^dd1/Tbx6^dd1 involves: C3HeB/FeJ * C57BL/6J	abnormal neural tube morphology	J:98216
Tbx6^dd1/Tbx6^dd1 involves: C3HeB/FeJ * C57BL/6J	abnormal paraxial mesoderm morphology	J:98216
Tbx6^em1Fzh/Tbx6⁺ FVB/NJ-Tbx6^em1Fzh	normal skeleton phenotype	J:271649
Tbx6^em1Fzh/Tbx6^em1Fzh FVB/NJ-Tbx6^em1Fzh	prenatal lethality, complete penetrance	J:271649
Tbx6^em1Fzh/Tbx6^em2Fzh FVB/NJ-Tbx6^em1Fzh Tbx6^em2Fzh	abnormal vertebrae development	J:271649
	rib fusion	J:271649
	vertebral fusion	J:271649
Tbx6^em2Fzh/Tbx6^em2Fzh FVB/NJ-Tbx6^em2Fzh	normal skeleton phenotype	J:271649
Tbx6^em3Fzh/Tbx6^em3Fzh C57BL/6J-Tbx6^em3Fzh	abnormal vertebrae morphology	J:288810
Tbx6^em3Fzh/Tbx6^em3Fzh C57BL/6J-Tbx6^em3Fzh	vertebral fusion	J:288810
Tbx6^tm1Pa/Tbx6^tm1Pa involves: 129S1/Sv * 129X1/SvJ	abnormal mesoderm development	J:217059
Tbx6^tm1Pa/Tbx6^tm1Pa involves: 129S1/Sv * 129X1/SvJ	abnormal neural tube morphology	J:217059
Tbx6^tm1Pa/Tbx6^tm1Pa involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal intersomitic artery morphology	J:80954
	abnormal paraxial mesoderm morphology	J:80954
	abnormal vascular development	J:80954
	embryonic lethality during organogenesis, complete penetrance	J:80954
	enlarged tail bud	J:80954
	hematoma	J:80954
	impaired somite development	J:80954
	kinked neural tube	J:80954
Tbx6^tm1Pa/Tbx6^tm2Pa involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR	abnormal direction of embryo turning	J:137163
	abnormal direction of heart looping	J:137163
	abnormal motile primary cilium morphology	J:137163

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24