About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tbx4
T-box 4
MGI:102556
41 phenotypes from 6 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Tbx4tm1(cre)Tmj/Tbx4tm1(cre)Tmj
Not Specified 		no abnormal phenotype detected J:177135
Tbx4tm1.1Kng/Tbx4+
involves: 129P2/OlaHsd * C57BL/6J * DBA/2 		abnormal patella morphology J:139169
abnormal pelvic girdle bone morphology J:139169
brachydactyly J:139169
short femur J:139169
short tibia J:139169
Tbx4tm1.1Kng/Tbx4tm1.1Kng
involves: 129P2/OlaHsd * C57BL/6J * DBA/2 		abnormal fibula morphology J:139169
abnormal limb development J:139169
abnormal patella morphology J:139169
abnormal pelvic girdle bone morphology J:139169
brachydactyly J:139169
fused tarsal bones J:139169
normal limbs/digits/tail phenotype J:139169
patellar dislocation J:139169
short femur J:139169
short tibia J:139169
Tbx4tm1.1Pa/Tbx4+
involves: 129S1/Sv * 129X1/SvJ 		delayed allantois development J:83256
delayed chorioallantoic fusion J:83256
Tbx4tm1.1Pa/Tbx4tm1.1Pa
involves: 129S1/Sv * 129X1/SvJ 		abnormal allantois morphology J:83256
abnormal umbilical artery morphology J:83256
abnormal vascular regression J:83256
absent umbilical cord J:83256
delayed allantois development J:83256
distended pericardium J:83256
embryonic lethality during organogenesis, complete penetrance J:83256
failure of chorioallantoic fusion J:83256
hemorrhage J:83256
increased allantois apoptosis J:83256
pericardial edema J:83256
small allantois J:83256
small hindlimb buds J:83256
Tbx4tm1.1Pa/Tbx4tm1.2Pa
Tg(Prrx1-cre)1Cjt/0
involves: 129 * C57BL/6J * FVB/N * SJL/J 		abnormal hindlimb morphology J:117423
abnormal ischium morphology J:117423
abnormal pelvic girdle bone morphology J:117423
brachydactyly J:117423
fused phalanges J:117423
fused tarsal bones J:117423
short femur J:117423
short fibula J:117423
Tbx4tm1.2Pa/Tbx4tm1.2Pa
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		no abnormal phenotype detected J:117423
Tbx4tm1.2Pa/Tbx4tm1.2Pa
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N 		abnormal autopod morphology J:117423
abnormal digit morphology J:117423
abnormal limb bud morphology J:117423
abnormal metatarsal bone morphology J:117423
abnormal pelvic girdle bone morphology J:117423
absent femur J:117423
embryonic lethality during organogenesis, complete penetrance J:117423
embryonic lethality during organogenesis, incomplete penetrance J:117423
failure of chorioallantoic fusion J:117423
fused phalanges J:117423
hindlimb oligodactyly J:117423
normal limbs/digits/tail phenotype J:117423
short femur J:117423
short fibula J:117423
short hindlimb J:117423
Tbx4tm1.2Pa/Tbx4tm1.2Pa
Tg(Prrx1-cre/ERT2)1Mlgn/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal hindlimb morphology J:157917
abnormal limb development J:157917
Tbx4tm1Pa/Tbx4+
involves: 129S1/Sv * 129X1/SvJ 		delayed allantois development J:83256
delayed chorioallantoic fusion J:83256
Tbx4tm1Pa/Tbx4tm1Pa
involves: 129S1/Sv * 129X1/SvJ 		abnormal allantois morphology J:83256
abnormal umbilical artery morphology J:83256
abnormal vascular regression J:83256
absent umbilical cord J:83256
delayed allantois development J:83256
distended pericardium J:83256
embryonic lethality during organogenesis, complete penetrance J:83256
failure of chorioallantoic fusion J:83256
hemorrhage J:83256
increased allantois apoptosis J:83256
pericardial edema J:83256
small allantois J:83256
small hindlimb buds J:83256
Tbx4tm4b(EUCOMM)Wtsi/Tbx4tm4b(EUCOMM)Wtsi
C57BL/6N-Tbx4tm4b(EUCOMM)Wtsi/Ucd 		abnormal embryo size J:211773
embryonic lethality prior to tooth bud stage J:211773
pale yolk sac J:211773
preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory