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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nmt1
N-myristoyltransferase 1
MGI:102579
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nmt1tm1.1Poru/Nmt1tm1.1Poru
Nmt2tm1.1Poru/Nmt2tm1.1Poru
Tg(Lck-cre)1Cwi/0
involves: C57BL/6 * DBA/2 * SJL 		abnormal CD4-positive, alpha beta T cell morphology J:226234
abnormal CD8-positive, alpha beta T cell morphology J:226234
decreased circulating interferon-gamma level J:226234
decreased circulating interleukin-2 level J:226234
decreased circulating tumor necrosis factor level J:226234
decreased DN4 thymocyte number J:226234
decreased double-positive T cell number J:226234
decreased interferon-gamma secretion J:226234
decreased interleukin-2 secretion J:226234
decreased single-positive T cell number J:226234
decreased splenocyte proliferation J:226234
decreased susceptibility to endotoxin shock J:226234
decreased T cell number J:226234
decreased T cell proliferation J:226234
normal immune system phenotype J:226234
increased double-negative T cell number J:226234
increased gamma-delta T cell number J:226234
increased T cell apoptosis J:226234
small thymus medulla J:226234
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory