Itga7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga7
integrin alpha 7
MGI:102700

26 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itga7^tm1Burk/Itga7^tm1Burk involves: 129S1/Sv * 129X1/SvJ	abnormal diaphragm morphology	J:187752
	abnormal muscle physiology	J:187752
	abnormal skeletal muscle fiber type ratio	J:187752
	centrally nucleated skeletal muscle fibers	J:187752
	embryonic lethality, incomplete penetrance	J:187752
	kyphosis	J:187752
	myopathy	J:187752
	premature death	J:187752
	skeletal muscle necrosis	J:187752
Itga7^tm1Burk/Itga7^tm1Burk involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal blood vessel morphology	J:100236
	abnormal vascular smooth muscle morphology	J:100236
	hemorrhage	J:100236
	intracranial hemorrhage	J:100236
	myopathy	J:100236
	prenatal lethality, incomplete penetrance	J:100236
	vascular smooth muscle hyperplasia	J:100236
	vascular smooth muscle hypertrophy	J:100236
Itga7^tm1Umr/Itga7^tm1Umr involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal diaphragm morphology	J:43840
	abnormal Schwann cell physiology	J:204174
	abnormal skeletal muscle morphology	J:43840, J:82116
	abnormal soleus morphology	J:43840
	centrally nucleated skeletal muscle fibers	J:43840
	dystrophic muscle	J:43840
	embryonic lethality during organogenesis, incomplete penetrance	J:43840
	increased circulating creatine kinase level	J:43840
	increased skeletal muscle fiber size	J:43840
	increased variability of skeletal muscle fiber size	J:43840
	muscle degeneration	J:43840
	skeletal muscle fiber atrophy	J:43840

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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