Lilrb4a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lilrb4a
leukocyte immunoglobulin-like receptor, subfamily B, member 4A
MGI:102701

18 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lilrb4a^tm1Eol/Lilrb4a^tm1Eol B6.129P2-Lilrb4a^tm1Eol	abnormal cellular extravasation	J:129969
	abnormal cytokine level	J:129969
	abnormal immune system cell morphology	J:129969
	abnormal immune system physiology	J:129969
	abnormal interferon level	J:129969
	abnormal interleukin level	J:129969
	abnormal leukocyte physiology	J:129969
	abnormal respiratory system physiology	J:129969
	decreased IgE level	J:129969
	increased inflammatory response	J:129969
	increased macrophage cell number	J:129969
	increased mast cell degranulation	J:129969
	increased plasma cell number	J:129969
Lilrb4a^tm1Eol/Lilrb4a^tm1Eol involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:64504
Lilrb4a^tm1Hrk/Lilrb4a^tm1Hrk involves: 129/Sv * BALB/c	abnormal mast cell physiology	J:70491
	increased mast cell degranulation	J:70491
	increased susceptibility to type I hypersensitivity reaction	J:70491
Lilrb4a^tm1Ttk/Lilrb4a^tm1Ttk B6.129X1-Lilrb4a^tm1Ttk	abnormal dendritic cell antigen presentation	J:141234
Lilrb4a^tm1Ttk/Lilrb4a^tm1Ttk B6.129X1-Lilrb4a^tm1Ttk	increased susceptibility to graft versus host disease	J:141234

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24