Vav2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vav2
vav 2 oncogene
MGI:102718

37 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vav2^tm1Kdf/Vav2^tm1Kdf B6.129S1-Vav2^tm1Kdf	abnormal iridocorneal angle	J:158008
	anterior iris synechia	J:158008
	ocular hypertension	J:158008
Vav2^tm1Kdf/Vav2^tm1Kdf involves: 129S1/Sv * C57BL/6	decreased B cell proliferation	J:69806
	decreased IgG3 level	J:69806
	decreased mature B cell number	J:69806
Vav2^tm1Tnr/Vav2^tm1Tnr involves: 129P2/OlaHsd	abnormal adrenal gland secretion	J:124056
	abnormal aorta tunica media morphology	J:124056
	abnormal bradykinin level	J:124056
	abnormal class switch recombination	J:69807
	abnormal heart morphology	J:124056
	abnormal physiological response to xenobiotic	J:124056
	adrenal medulla hyperplasia	J:124056
	cardiac fibrosis	J:124056
	decreased B cell number	J:69807
	decreased B cell proliferation	J:69807
	decreased creatinine clearance	J:124056
	decreased IgG1 level	J:69807
	decreased IgG2b level	J:69807
	decreased IgG3 level	J:69807
	decreased IgM level	J:69807
	decreased spleen germinal center number	J:69807
	decreased urine sodium level	J:124056
	enlarged adrenal medulla	J:124056
	heart left ventricle hypertrophy	J:124056
	hydrocephaly	J:124056
	hypertension	J:124056
	increased circulating adrenaline level	J:124056
	increased circulating aldosterone level	J:124056
	increased circulating antidiuretic hormone level	J:124056
	increased circulating noradrenaline level	J:124056
	increased circulating renin level	J:124056
	increased heart rate	J:124056
	increased mean systemic arterial blood pressure	J:124056
	increased myocardial fiber size	J:124056
	increased renin activity	J:124056
	oliguria	J:124056
	renal fibrosis	J:124056
	vascular smooth muscle hyperplasia	J:124056

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24