Ednrb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ednrb
endothelin receptor type B
MGI:102720

102 phenotypes from 46 alleles in 23 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ednrb^s+Ms/Ednrb^s+Ms JF1/Ms-Ednrb^s+Ms/Ms	normal pigmentation phenotype	J:199278
Ednrb^s-1Acrg/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-1Acrg/Ednrb^s-1Acrg involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:16291, J:100221
Ednrb^s-1Acrg/Ednrb^s-9ThW involves: 101/Rl * C3H/Rl * C57BL/6J	abnormal diaphragm morphology	J:87686
	abnormal neuromuscular synapse morphology	J:87686
	abnormal phrenic nerve morphology	J:87686
	respiratory distress	J:87686
Ednrb^s-1Acrg/Ednrb^s-48UThc involves: 101/Rl * C3H/Rl * C57BL/6J	normal muscle phenotype	J:87686
	normal nervous system phenotype	J:87686
	normal respiratory system phenotype	J:87686
Ednrb^s-1Chlc/Ednrb^s-1Chlc involves: 101/Rl * C3H/Rl	megacolon	J:10322, J:44601, J:100221
	postnatal lethality, incomplete penetrance	J:10322, J:16291, J:44601, J:100221
	white spotting	J:10322, J:16291, J:44601, J:100221
Ednrb^s-1MLPf/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-1MLPf/Ednrb^s-1MLPf involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:24557, J:100221
Ednrb^s-1Pu/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-1Pu/Ednrb^s-1Pu involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-1XMLP/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-1XMLP/Ednrb^s-1XMLP involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-1XMLPc/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-1XMLPc/Ednrb^s-1XMLPc involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-2Btlr/Ednrb^s-2Btlr C57BL/6J-Ednrb^s-2Btlr	lethality at weaning	J:215823
Ednrb^s-2Btlr/Ednrb^s-2Btlr C57BL/6J-Ednrb^s-2Btlr	variable body spotting	J:215823
Ednrb^s-2CHLd/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-2CHLd/Ednrb^s-2CHLd involves: 101/Rl * C3H/Rl	preweaning lethality, complete penetrance	J:10322, J:100221
Ednrb^s-2Etopc/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-2Etopc/Ednrb^s-2Etopc involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-2MLPl/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-2MLPl/Ednrb^s-2MLPl involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-3Btlr/Ednrb^s-3Btlr C57BL/6J-Ednrb^s-3Btlr	belly spot	J:264716
Ednrb^s-3Etopf/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-3Etopf/Ednrb^s-3Etopf involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-4Blec/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-4Blec/Ednrb^s-4Blec involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-4Chlc/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-4Chlc/Ednrb^s-4Chlc involves: 101/Rl * C3H/Rl	preweaning lethality, complete penetrance	J:10322, J:16291, J:100221
Ednrb^s-4Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-4Pub/Ednrb^s-4Pub involves: 101/Rl * C3H/Rl	preweaning lethality, complete penetrance	J:16291, J:100221
Ednrb^s-9ThW/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-9ThW/Ednrb^s-9ThW involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-12MNURn/Ednrb^s-12MNURn involves: 101/Rl * C3H/Rl	postnatal lethality, complete penetrance	J:100221
Ednrb^s-12MNURn/Ednrb^s-12MNURn involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s-13Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-13Pub/Ednrb^s-13Pub involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-15DttMb/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-15DttMb/Ednrb^s-15DttMb involves: 101/Rl * C3H/Rl	abnormal brain morphology	J:125702
	abnormal nervous system morphology	J:100221, J:125702
	abnormal skeleton morphology	J:100221
	neonatal lethality, complete penetrance	J:16291, J:100221
Ednrb^s-15DttMb/Ednrb^s-15DttMb involves: 101/Rl * C3H/Rl * C57BL/6J	abnormal diaphragm morphology	J:87686
	abnormal phrenic nerve morphology	J:87686
Ednrb^s-15DttMb/Ednrb^s involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-15DttMb/Ednrb^s involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s-17FrS/Ednrb^s-17FrS involves: 101/Rl * C3H/Rl	megacolon	J:44601, J:100221
	postnatal lethality, complete penetrance	J:44601, J:100221
	white spotting	J:44601, J:100221
Ednrb^s-17Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-17Pub/Ednrb^s-17Pub involves: 101/Rl * C3H/Rl	preweaning lethality, complete penetrance	J:16291, J:100221
Ednrb^s-24Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-24Pub/Ednrb^s-24Pub involves: 101/Rl * C3H/Rl	preweaning lethality, complete penetrance	J:16291, J:100221
Ednrb^s-27Pu/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-27Pu/Ednrb^s-27Pu involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-27Pub/Ednrb^s-27Pub involves: 101/Rl * C3H/Rl	megacolon	J:44601, J:100221
	postnatal lethality, complete penetrance	J:16291, J:44601, J:100221
	white spotting	J:16291, J:44601, J:100221
Ednrb^s-29Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-29Pub/Ednrb^s-29Pub involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-36Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-36Pub/Ednrb^s-36Pub B6.Cg-Ednrb^s-36Pub	abnormal bone ossification	J:125229
	abnormal palatal rugae morphology	J:125229
	abnormal secondary palate development	J:125229
	abnormal soft palate morphology	J:125229
	absent palatine bone horizontal plate	J:125229
	cleft secondary palate	J:125229
	cleft upper lip	J:125229
	failure of palatal shelf elevation	J:125229
	increased cell proliferation	J:125229
	increased mitotic index	J:125229
	maxillary shelf hypoplasia	J:125229
Ednrb^s-36Pub/Ednrb^s-36Pub involves: 101/Rl * C3H/Rl	abnormal cartilage morphology	J:100221
	abnormal nervous system morphology	J:100221
	abnormal skeleton morphology	J:100221
	neonatal lethality, complete penetrance	J:16291, J:100221
Ednrb^s-48UThc/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-48UThc/Ednrb^s-48UThc involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-52Pub/Ednrb⁺ involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s-52Pub/Ednrb^s-52Pub involves: 101/Rl * C3H/Rl	prenatal lethality, complete penetrance	J:100221
Ednrb^s-136H/Ednrb^s-136H involves: 101/H * C3H/HeH	belly spot	J:180879
	head spot	J:180879
	white spotting	J:180879
Ednrb^s-160H/Ednrb^s-160H involves: C3H/HeH	white spotting	J:181531
Ednrb^s-161H/Ednrb^s-161H involves: C3H/HeH	white spotting	J:181531
Ednrb^s-162H/Ednrb^s-162H involves: C3H/HeH	decreased body size	J:180879
Ednrb^s-162H/Ednrb^s-162H involves: C3H/HeH	white spotting	J:180879, J:181531
Ednrb^s-Btlr/Ednrb^s-Btlr C57BL/6J-Ednrb^s-Btlr	lethality at weaning, complete penetrance	J:202015
Ednrb^s-Btlr/Ednrb^s-Btlr C57BL/6J-Ednrb^s-Btlr	variable body spotting	J:202015
Ednrb^s-l/Ednrb^s-l involves: C3H/HeJ * C57BL/6	abnormal coat/hair pigmentation	J:5008
	abnormal cochlear hair cell morphology	J:5048
	abnormal cochlear sensory epithelium morphology	J:5048
	abnormal Deiters cell morphology	J:5048
	abnormal enteric nervous system morphology	J:5008
	abnormal hindgut morphology	J:5407
	abnormal inner ear morphology	J:5048
	abnormal pigmentation pattern	J:5008
	abnormal stria vascularis morphology	J:5048
	absent enteric neurons	J:5008
	megacolon	J:5008
	postnatal lethality	J:5008
	premature death	J:5008
	preweaning lethality, incomplete penetrance	J:5008
Ednrb^s-l/Ednrb^s-l involves: C57BL/6J * SSL/Le	abnormal coat/hair pigmentation	J:19441
	abnormal melanocyte proliferation	J:19441
	abnormal pigmentation pattern	J:19441
Ednrb^s/Ednrb^s-1Acrg involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-1Acrg involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-1Chlc involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-1MLPf involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-1MLPf involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-1Pu involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-1Pu involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-1XMLP involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-1XMLP involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-1XMLPc involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-1XMLPc involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-2CHLd involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-2CHLd involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-2Etopc involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-2Etopc involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-2MLPl involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-2MLPl involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-3Etopf involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-3Etopf involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-4Blec involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-4Blec involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-4Chlc involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-4Chlc involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-4Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-4Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-9ThW involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-9ThW involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-12MNURn involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-13Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-13Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-17FrS involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-17Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-17Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-24Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-24Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-27Pu involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-27Pu involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-27Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-29Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-29Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-36Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-36Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-48UThc involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-48UThc involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s-52Pub involves: 101/Rl * C3H/Rl	decreased body size	J:100221
Ednrb^s/Ednrb^s-52Pub involves: 101/Rl * C3H/Rl	white spotting	J:100221
Ednrb^s/Ednrb^s Not Specified	abnormal foot pigmentation	J:30758
	abnormal tail pigmentation	J:30758
	megacolon	J:15014
	variable body spotting	J:12952, J:30758
	variable depigmentation	J:30758
	white spotting	J:12952
Ednrb^tm1(tTA)Tilg/Ednrb^{tm3(tetO)Tilg} involves: 129P2/OlaHsd * 129S1/Sv	abnormal enteric neuron morphology	J:58698
	absent coat pigmentation	J:58698
	normal digestive/alimentary phenotype	J:58698
	megacolon	J:58698
	normal pigmentation phenotype	J:58698
Ednrb^tm1.1Nrd/Ednrb⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal blood pH regulation	J:226561
	abnormal oxygen level	J:226561
	decreased circulating lactate level	J:226561
	decreased response of heart to induced stress	J:226561
	hypocapnia	J:226561
	increased cardiac output	J:226561
	increased heart ventricle muscle contractility	J:226561
	increased mean systemic arterial blood pressure	J:226561
Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal coat/hair pigmentation	J:226561
	cachexia	J:226561
	decreased body size	J:226561
	lethality at weaning, complete penetrance	J:226561
	megacolon	J:226561
	white spotting	J:226561
Ednrb^tm1.1Yko/Ednrb^tm1.1Yko involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL	decreased vasodilation	J:135711
	intestinal obstruction	J:135711
	postnatal lethality, complete penetrance	J:135711
	white spotting	J:135711
Ednrb^tm1Myks/Ednrb^tm1Myks involves: 129P2/OlaHsd	abnormal cell migration	J:84057
	absent coat pigmentation	J:84057
	megacolon	J:84057
	premature death	J:84057
Ednrb^tm1Nrd/Ednrb^tm1Nrd Tg(Dct-lacZ)#Ove/0 Tg(Tyr-cre/ERT2)13Bos/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal epidermal melanocyte morphology	J:231435
	decreased melanocyte number	J:231435
Ednrb^tm1Yko/Ednrb^tm1Yko Tg(AQP2-cre)2Dek/0 involves: C57BL/6 * CBA	abnormal urine homeostasis	J:116002
	abnormal urine sodium level	J:116002
	decreased renin activity	J:116002
	increased systemic arterial blood pressure	J:116002
	increased systemic arterial diastolic blood pressure	J:116002
	increased systemic arterial systolic blood pressure	J:116002
	oliguria	J:116002
Ednrb^tm1Yko/Ednrb^tm1Yko Tg(Tek-cre)1Ywa/0 involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL	abnormal blood homeostasis	J:135711
	abnormal nitric oxide homeostasis	J:135711
	normal cardiovascular system phenotype	J:135711
	decreased vasodilation	J:135711
Ednrb^tm1Ywa/Ednrb⁺ involves: 129S/SvEvBrd	decreased acute inflammation	J:103977
Ednrb^tm1Ywa/Ednrb⁺ involves: 129S/SvEvBrd	hypoalgesia	J:103977
Ednrb^tm1Ywa/Ednrb^s involves: 129S/SvEv	abnormal blood gas level	J:60070
	hypercapnia	J:60070
	hypoxia	J:60070
	increased mean systemic arterial blood pressure	J:60070
Ednrb^tm1Ywa/Ednrb^tm1Ywa B6;129-Ednrb^tm1Ywa/J	abnormal colon goblet cell morphology	J:216833
	abnormal colon morphology	J:216833
	abnormal intestinal mucosa morphology	J:216833
	abnormal intestine physiology	J:216833
	abnormal large intestine crypts of Lieberkuhn morphology	J:216833
	decreased feces water content	J:216833
Ednrb^tm1Ywa/Ednrb^tm1Ywa involves: 129S5/SvEvBrd	abnormal choroid pigmentation	J:22206
	abnormal coat/hair pigmentation	J:22206
	abnormal hair follicle melanocyte morphology	J:22206
	aganglionic megacolon	J:22206
	cachexia	J:22206
	decreased acute inflammation	J:103977
	hypoalgesia	J:103977
	intestinal obstruction	J:22206
	postnatal growth retardation	J:22206
	premature death	J:22206
	variable depigmentation	J:22206
	white spotting	J:22206
Ednrb^{tm2(rtTA)Tilg}/Ednrb^{tm3(tetO)Tilg} involves: 129P2/OlaHsd * 129S1/Sv	abnormal enteric neuron morphology	J:58698
	absent coat pigmentation	J:58698
	normal digestive/alimentary phenotype	J:58698
	megacolon	J:58698
	normal pigmentation phenotype	J:58698
	premature death	J:58698
Ednrb^WS4/Ednrb^WS4 involves: BALB/c * MSM	abnormal cochlea morphology	J:76584
	abnormal hearing physiology	J:76584
	abnormal stria vascularis morphology	J:76584
	absent strial intermediate cells	J:76584
	cochlear hair cell degeneration	J:76584
	deafness	J:76584
	megacolon	J:76584
	organ of Corti degeneration	J:76584
	premature death	J:76584
	thin stria vascularis	J:76584
	variable body spotting	J:76584

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24