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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zbtb7b
zinc finger and BTB domain containing 7B
MGI:102755
18 phenotypes from 17 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tg(CD2-Zbtb7b)C8Rbo/?
involves: C57BL/6 		absent CD8-positive, alpha-beta T cells J:97610
increased CD4-positive, alpha-beta T cell number J:97610
Tg(CD4-Zbtb7b*,-GFP)1Itan/?
Not Specified 		no abnormal phenotype detected J:141142
Zbtb7bhd/Zbtb7bhd
involves: 129/Sv * BALB/c * C3H * C57BL/6 		abnormal CD4-positive T cell differentiation J:48734
absent CD4-positive, alpha-beta T cells J:48734
increased CD8-positive, alpha-beta T cell number J:48734
reduced female fertility J:48734
Zbtb7bhpls/Zbtb7bhpls
involves: C57BL/6JAnu 		abnormal humoral immune response J:104190
decreased CD4-positive, alpha-beta T cell number J:104190
Zbtb7btm1.1Rbo/Zbtb7btm1.1Rbo
Not Specified 		abnormal CD8-positive, alpha-beta T cell number J:141145
abnormal T cell differentiation J:141145
decreased CD4-positive, alpha-beta T cell number J:141145
Zbtb7btm1.1Skok/Zbtb7btm1.1Skok
involves: 129/Sv * C57BL/6 		decreased CD4-positive, alpha-beta T cell number J:169841
Zbtb7btm1Itan/Zbtb7btm1Tani
involves: 129 * C57BL/6 		abnormal CD4-positive, alpha beta T cell morphology J:141142
abnormal CD4-positive, alpha-beta T cell physiology J:141142
decreased CD4-positive, alpha-beta T cell number J:141142
increased CD8-positive, alpha-beta T cell number J:141142
increased double-negative T cell number J:141142
Zbtb7btm1Itan/Zbtb7btm2Itan
involves: 129 * C57BL/6 		decreased CD4-positive, alpha-beta T cell number J:141142
increased CD8-positive, alpha-beta T cell number J:141142
increased double-negative T cell number J:141142
Zbtb7btm1Litt/Zbtb7btm1.2Litt
involves: C57BL/6 		abnormal double-positive T cell morphology J:141144
decreased CD4-positive, alpha-beta T cell number J:141144
increased CD8-positive, alpha-beta T cell number J:141144
increased interferon-gamma secretion J:141144
Zbtb7btm1Tani/Zbtb7btm1Tani
involves: 129 * C57BL/6 		increased double-negative T cell number J:141142
Zbtb7btm2Itan/Zbtb7b+
involves: 129 * C57BL/6 		no abnormal phenotype detected J:141142
Zbtb7btm2Litt/Zbtb7btm1.2Litt
involves: 129P2/OlaHsd 		decreased CD4-positive, alpha-beta T cell number J:141144
Zbtb7btm2Litt/Zbtb7btm1.2Litt
Tg(Lck-cre)1Cwi/?
involves: 129P2/OlaHsd * C57BL/6 		abnormal T cell differentiation J:141144
decreased CD4-positive, alpha-beta T cell number J:141144
Zbtb7btm2Litt/Zbtb7btm2Litt
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		absent CD4-positive, alpha-beta T cells J:141519
Zbtb7btm2Tani/Zbtb7b+
Not Specified 		decreased CD8-positive, alpha-beta T cell number J:131081
Zbtb7btm3Itan/Zbtb7btm3Itan
Not Specified 		no abnormal phenotype detected J:141142
Zbtb7btm4.1Itan/Zbtb7btm4.1Itan
Not Specified 		decreased CD4-positive, alpha-beta T cell number J:193321
increased CD8-positive, alpha-beta T cell number J:193321
Zbtb7btm6.1Itan/Zbtb7btm6.1Itan
Tg(Cd4-cre)1Cwi/?
involves: C57BL/6 * DBA/2 		decreased CD8-positive, alpha-beta T cell number J:195348
Zbtb7btm6.1Itan/Zbtb7btm6.1Itan
Tg(Cd8a-cre)1Itan/?
involves: C57BL/6 		normal immune system phenotype J:195348
Zbtb7btm7Itan/Zbtb7btm7Itan
Not Specified 		decreased CD4-positive, alpha-beta T cell number J:195348
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory