Rab18 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rab18
RAB18, member RAS oncogene family
MGI:102790

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rab18^{Gt(EUCE0233a03)Hmgu}/Rab18⁺ involves: 129P2/OlaHsd * C57BL/6J	perinatal lethality, incomplete penetrance	J:211808
Rab18^{Gt(EUCE0233a03)Hmgu}/Rab18^{Gt(EUCE0233a03)Hmgu} involves: 129P2/OlaHsd * C57BL/6J	abnormal cell cytoskeleton morphology	J:211808
	abnormal eye development	J:211808
	abnormal nervous system morphology	J:211808
	abnormal neuromuscular synapse morphology	J:211808
	abnormal pupil morphology	J:211808
	abnormal pupillary reflex	J:211808
	abnormal sciatic nerve morphology	J:211808
	increased white fat cell lipid droplet size	J:211808
	limb grasping	J:211808
	miotic pupil	J:211808
	nuclear cataract	J:211808
	perinatal lethality, incomplete penetrance	J:211808
	weakness	J:211808
Rab18^m1Hongc/Rab18^m1Hongc C57BL/6J-Rab18^m1Hongc	abnormal corpus callosum morphology	J:220974
	abnormal dorsal spinal root morphology	J:220974
	abnormal gait	J:220974
	ataxia	J:220974
	axon degeneration	J:220974
	decreased body weight	J:220974
	hyporesponsive to tactile stimuli	J:220974
	impaired coordination	J:220974
	increased thermal nociceptive threshold	J:220974
	limb grasping	J:220974
	microphthalmia	J:220974
	optic nerve degeneration	J:220974
	small testis	J:220974

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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