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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fstl1
follistatin-like 1
MGI:102793
90 phenotypes from 10 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fstl1Gt(P086B03)Wrst/Fstl1Gt(P086B03)Wrst
involves: 129S2/SvPas * ICR 		no abnormal phenotype detected J:238836
Fstl1tm1.1Mvdh/Fstl1tm1.1Mvdh
Tg(Myh6-cre)2182Mds/0
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal coronary vessel morphology J:177416
abnormal heart septum morphology J:177416
cardiac fibrosis J:177416
cardiac hypertrophy J:177416
decreased angiogenesis J:177416
decreased heart left ventricle muscle contractility J:177416
increased heart left ventricle size J:177416
increased heart left ventricle weight J:177416
increased heart weight J:177416
increased myocardial fiber size J:177416
increased response of heart to induced stress J:177416
pulmonary vascular congestion J:177416
Fstl1tm1.1Ning/Fstl1tm1.1Ning
involves: 129S4/SvJae * C57BL/6J * FVB/N 		abnormal breathing pattern J:171347
abnormal bronchiole morphology J:171347
abnormal larynx morphology J:171347
abnormal lung development J:171347
abnormal lung epithelium morphology J:171347
abnormal lung morphology J:171347
abnormal neural tube morphology J:171347
abnormal pulmonary alveolar sac morphology J:171347
abnormal skeleton morphology J:171347
abnormal trachea morphology J:171347
abnormal tracheal cartilage morphology J:171347
abnormal tracheal ciliated epithelium morphology J:171347
abnormal type II pneumocyte morphology J:171347
cyanosis J:171347
decreased alveolar lamellar body number J:171347
decreased surfactant secretion J:171347
decreased tracheal cartilage ring number J:171347
decreased type I pneumocyte number J:171347
hydroureter J:171347
increased glycogen level J:171347
increased type II pneumocyte number J:171347
neonatal lethality, complete penetrance J:171347
primary atelectasis J:171347
pulmonary hyperplasia J:171347
trachea stenosis J:171347
Fstl1tm1.1Nju/Fstl1tm1.1Nju
involves: 129 * C57BL/6 * FVB/N 		abnormal kidney pelvis morphology J:187117
abnormal ureter development J:187117
abnormal ureter morphology J:187117
abnormal ureter urothelium morphology J:187117
dilated ureter J:187117
hydronephrosis J:187117
hydroureter J:187117
kidney papillary atrophy J:187117
small kidney J:187117
ureter stenosis J:187117
Fstl1tm1.2Mvdh/Fstl1+
involves: 129S4/SvJae * C57BL/6 * FVB 		abnormal rib morphology J:176532
asymmetric sternocostal joints J:176532
Fstl1tm1.2Mvdh/Fstl1tm1.2Mvdh
involves: 129S4/SvJae * C57BL/6 * FVB 		abnormal bronchiole morphology J:176532
abnormal cervical atlas morphology J:176532
abnormal cervical axis morphology J:176532
abnormal costal cartilage morphology J:176532
abnormal digit morphology J:176532
abnormal hindlimb stylopod morphology J:176532
abnormal hindlimb zeugopod morphology J:176532
abnormal lung lobe morphology J:176532
abnormal metacarpal bone morphology J:176532
abnormal pulmonary alveolus morphology J:176532
abnormal rib morphology J:176532
abnormal spine curvature J:176532
abnormal tracheal cartilage morphology J:176532
absent patella J:176532
absent sesamoid bone of gastrocnemius J:176532
asymmetric sternocostal joints J:176532
bowed fibula J:176532
camptomelia J:176532
cyanosis J:176532
decreased bone ossification J:176532
fused phalanges J:176532
lordokyphosis J:176532
perinatal lethality, complete penetrance J:176532
primary atelectasis J:176532
respiratory distress J:176532
Fstl1tm1Ajn/Fstl1tm1Ajn
B6.Cg-Fstl1tm1Ajn 		abnormal lung hysteresivity J:322116
abnormal lung volume J:322116
abnormal respiratory system physiology J:322116
decreased lung elastance J:322116
emphysema J:322116
increased lung apoptosis J:322116
increased lung compliance J:322116
Fstl1tm1b(EUCOMM)Hmgu/Fstl1tm1b(EUCOMM)Hmgu
C57BL/6N-Fstl1tm1b(EUCOMM)Hmgu/H 		decreased fasting circulating glucose level J:211773
decreased neutrophil cell number J:211773
impaired glucose tolerance J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
increased lymphocyte cell number J:211773
Fstl1tm1Nju/Fstl1tm1Nju
Tg(Scn10a-cre)1Rkun/0
involves: 129 * C57BL/6 * DBA 		abnormal action potential J:188549
abnormal dorsal root ganglion morphology J:188549
decreased chemical nociceptive threshold J:188549
decreased thermal nociceptive threshold J:188549
hyperresponsive to tactile stimuli J:188549
increased excitatory postsynaptic current frequency J:188549
Fstl1tm2.1(cre/ERT2)Mvdh/Fstl1+
involves: 129P2/OlaHsd * C57BL/6 		abnormal rib morphology J:176532
asymmetric sternocostal joints J:176532
Fstl1tm2.1(cre/ERT2)Mvdh/Fstl1tm2.1(cre/ERT2)Mvdh
involves: 129P2/OlaHsd * C57BL/6 		abnormal bronchiole morphology J:176532
abnormal costal cartilage morphology J:176532
abnormal lung lobe morphology J:176532
abnormal pulmonary alveolus morphology J:176532
abnormal rib morphology J:176532
abnormal tracheal cartilage morphology J:176532
asymmetric sternocostal joints J:176532
camptomelia J:176532
cyanosis J:176532
fused phalanges J:176532
perinatal lethality, complete penetrance J:176532
primary atelectasis J:176532
respiratory distress J:176532
Tg(Ckm-Fstl1)#Mvdh/0
involves: C57BL/6 		abnormal coronary vessel morphology J:177416
cardiac fibrosis J:177416
decreased cardiac muscle contractility J:177416
decreased response of heart to induced stress J:177416
increased angiogenesis J:177416
increased heart left ventricle weight J:177416
increased heart weight J:177416
increased myocardial fiber size J:177416
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory