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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lmo2
LIM domain only 2
MGI:102811
30 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lmo2tm1Thr/Lmo2tm1Thr
either: (involves: 129P2/OlaHsd * MF1) or (involves: 129/Sv * 129P2/OlaHsd) 		abnormal allantois morphology J:19175
abnormal cell death J:19175
abnormal dorsal aorta morphology J:19175
abnormal embryonic hematopoiesis J:19175
abnormal neural tube morphology J:19175
absent visceral yolk sac blood islands J:19175
decreased embryo size J:19175
delayed embryo turning J:19175
delayed somite formation J:19175
distended pericardium J:19175
embryonic lethality during organogenesis, complete penetrance J:19175
pale yolk sac J:19175
pallor J:19175
short rostral-caudal axis J:19175
small visceral yolk sac J:19175
Lmo2tm2(cre)Thr/Lmo2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal common myeloid progenitor cell morphology J:155870
abnormal megakaryocyte progenitor cell morphology J:155870
decreased erythrocyte cell number J:155870
decreased granulocyte number J:155870
decreased hemoglobin content J:155870
decreased monocyte cell number J:155870
increased mean corpuscular volume J:155870
thrombocytopenia J:155870
Lmo2tm3Thr/Lmo2tm4Thr
Cd19tm1(cre)Thr/Cd19+
involves: 129S/SvEv 		normal hematopoietic system phenotype J:86869
normal immune system phenotype J:86869
Lmo2tm3Thr/Lmo2tm4Thr
Rag1tm1(cre)Thr/Rag1+
involves: 129S/SvEv 		normal hematopoietic system phenotype J:86869
normal immune system phenotype J:86869
Lmo2tm3Thr/Lmo2tm4Thr
Tg(Lck-cre)1Thr/0
involves: 129S/SvEv 		normal hematopoietic system phenotype J:86869
normal immune system phenotype J:86869
Lmo2tm4Thr/Lmo2tm4Thr
involves: 129S/SvEv 		prenatal lethality J:59368
Tg(CD2-Lmo2)#Thr/0
involves: C57BL/6 * CBA 		enlarged spleen J:102058
enlarged thymus J:102058
increased acute lymphoblastic leukemia incidence J:102058
premature death J:102058
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory