Vcan Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vcan
versican
MGI:102889

53 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vcan^em1Hwat/Vcan^em1Hwat involves: C57BL/6N	abnormal dermal layer morphology	J:298045
	absent epidermis	J:298045
	decreased embryo size	J:298045
	normal embryo phenotype	J:298045
	enhanced wound healing	J:298045
	hemorrhage	J:298045
	hindlimb syndactyly	J:298045
	lethality throughout fetal growth and development, incomplete penetrance	J:298045
	normal reproductive system phenotype	J:298045
Vcan^em2(IMPC)Mbp/Vcan⁺ C57BL/6NCrl-Vcan^em2(IMPC)Mbp/Mmucd	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged spleen	J:211773
	eye hemorrhage	J:211773
	microphthalmia	J:211773
	persistence of hyaloid vascular system	J:211773
Vcan^em2(IMPC)Mbp/Vcan^em2(IMPC)Mbp C57BL/6NCrl-Vcan^em2(IMPC)Mbp/Mmucd	abnormal embryo turning	J:211773
	abnormal heart looping	J:211773
	abnormal heart morphology	J:211773
	abnormal neural tube morphology	J:211773
	abnormal optic vesicle formation	J:211773
	abnormal pharyngeal arch morphology	J:211773
	abnormal somite shape	J:211773
	abnormal visceral yolk sac morphology	J:211773
	abnormal vitelline vasculature morphology	J:211773
	embryonic growth retardation	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Vcan^{Tg(Hoxa1)1Chm}/Vcan^{Tg(Hoxa1)1Chm} involves: C57BL/6J * CBA	abnormal heart development	J:41016
	abnormal heart right ventricle morphology	J:41016
	absent atrioventricular cushions	J:41016
	absent conotruncal ridges	J:41016
	decreased embryo size	J:41016
	dilated heart	J:41016
	dilated heart atrium	J:41016
	dilated heart left ventricle	J:41016
	embryonic lethality during organogenesis, complete penetrance	J:41016
Vcan^tm1.1Dzim/Vcan^tm1.1Dzim involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	abnormal axon morphology	J:150124
	normal nervous system phenotype	J:150124
Vcan^tm1.1Hwat/Vcan^tm1.1Hwat involves: C57BL/6	no abnormal phenotype detected	J:165936
Vcan^tm1.1Hwat/Vcan^tm1.1Hwat Tg(Prrx1-cre)1Cjt/0 involves: C57BL/6 * C57BL/6J * SJL/J	abnormal autopod morphology	J:165936
	abnormal chondrocyte physiology	J:165936
	abnormal digit morphology	J:165936
	abnormal phalanx morphology	J:165936
	short limbs	J:165936
Vcan^tm2Hwat/Vcan^tm2Hwat B6.Cg-Vcan^tm2Hwat	embryonic lethality during organogenesis, complete penetrance	J:225115
Vcan^tm2Hwat/Vcan^tm2Hwat involves: 129 * BALB/c * C57BL/6	abnormal cardiovascular system physiology	J:225115
	abnormal interventricular septum morphology	J:225115
	cyanosis	J:225115
	decreased atrioventricular cushion size	J:225115
	decreased fetal size	J:225115
	embryonic lethality during organogenesis, incomplete penetrance	J:225115
	neonatal lethality, complete penetrance	J:225115
	ventricular septal defect	J:225115
Vcan^tm2Hwat/Vcan^tm2Hwat involves: 129 * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:225115

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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